相似文献
1
Synthetic studies on the bryostatins: preparation of a truncated BC-ring intermediate by pyran annulation.
Org Lett. 2005 May 26;7(11):2149-52. doi: 10.1021/ol050511w.
2
Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core.
Org Lett. 2005 May 26;7(11):2153-6. doi: 10.1021/ol050512o.
3
Total syntheses of bryostatins: synthesis of two ring-expanded bryostatin analogues and the development of a new-generation strategy to access the C7-C27 fragment.
Chemistry. 2011 Aug 22;17(35):9789-805. doi: 10.1002/chem.201002932. Epub 2011 Jul 21.
4
Convergent assembly of highly potent analogues of bryostatin 1 via pyran annulation: bryostatin look-alikes that mimic phorbol ester function.
J Am Chem Soc. 2008 May 28;130(21):6660-1. doi: 10.1021/ja8022169. Epub 2008 May 2.
5
Enantioselective reductive coupling of alkynes and alpha-keto aldehydes via rhodium-catalyzed hydrogenation: an approach to bryostatin substructures.
Org Lett. 2006 Mar 2;8(5):891-4. doi: 10.1021/ol052976s.
6
Synthesis of the bryostatin 1 northern hemisphere (C1-C16) via desymmetrization by ketalization/ring-closing metathesis.
Org Lett. 2004 Oct 28;6(22):4045-8. doi: 10.1021/ol0483044.
7
Synthetic studies toward the bryostatins: a substrate-controlled approach to the A-ring.
Org Lett. 2006 Aug 17;8(17):3667-70. doi: 10.1021/ol061173h.
8
Enantioselective synthesis of pladienolide B and truncated analogues as new anticancer agents.
Org Lett. 2013 Jul 19;15(14):3610-3. doi: 10.1021/ol401458d. Epub 2013 Jul 3.
9
Enantioselective formal total synthesis of the antitumor macrolide bryostatin 7.
Org Lett. 2006 Sep 28;8(20):4477-80. doi: 10.1021/ol061626i.
10
A new synthetic approach to the C ring of known as well as novel bryostatin analogues.
Org Lett. 2003 Nov 27;5(24):4549-52. doi: 10.1021/ol0355332.
引用本文的文献
1
Anticancer Activity of the Marine-Derived Compound Bryostatin 1: Preclinical and Clinical Evaluation.
Int J Mol Sci. 2025 Aug 11;26(16):7765. doi: 10.3390/ijms26167765.
2
Deletion of the C26 Methyl Substituent from the Bryostatin Analogue Merle 23 Has Negligible Impact on Its Biological Profile and Potency.
Chembiochem. 2018 May 18;19(10):1049-1059. doi: 10.1002/cbic.201700677. Epub 2018 Apr 27.
3
Synthesis and Biological Evaluation of Fluorescent Bryostatin Analogues.
Chembiochem. 2018 Apr 16;19(8):877-889. doi: 10.1002/cbic.201700655. Epub 2018 Mar 25.
4
Scalable synthesis of bryostatin 1 and analogs, adjuvant leads against latent HIV.
Science. 2017 Oct 13;358(6360):218-223. doi: 10.1126/science.aan7969.
5
Replacement of the Bryostatin A- and B-Pyran Rings With Phenyl Rings Leads to Loss of High Affinity Binding With PKC.
Tetrahedron Lett. 2016 Oct 19;57(42):4749-4753. doi: 10.1016/j.tetlet.2016.09.040.
6
Synthesis of a des-B-ring bryostatin analogue leads to an unexpected ring expansion of the bryolactone core.
J Am Chem Soc. 2014 Sep 24;136(38):13202-8. doi: 10.1021/ja5078188. Epub 2014 Sep 10.
7
Mechanistic and computational studies of exocyclic stereocontrol in the synthesis of bryostatin-like cis-2,6-disubstituted 4-alkylidenetetrahydropyrans by Prins cyclization.
J Org Chem. 2013 Jan 4;78(1):104-15. doi: 10.1021/jo301953h. Epub 2012 Nov 7.
8
Translating Nature's Library: The Bryostatins and Function-Oriented Synthesis.
Isr J Chem. 2011 Apr 1;51(3-4):453-472. doi: 10.1002/ijch.201100020. Epub 2011 Mar 24.
9
Role of the C8 gem-dimethyl group of bryostatin 1 on its unique pattern of biological activity.
Bioorg Med Chem Lett. 2012 Jun 15;22(12):4084-8. doi: 10.1016/j.bmcl.2012.04.073. Epub 2012 Apr 24.
10
Total synthesis of bryostatins: the development of methodology for the atom-economic and stereoselective synthesis of the ring C subunit.
Chemistry. 2011 Aug 22;17(35):9762-76. doi: 10.1002/chem.201002898. Epub 2011 Jul 26.
本文引用的文献
1
Synthetic studies on the bryostatins: synthetic routes to analogues containing the tricyclic macrolactone core.
Org Lett. 2005 May 26;7(11):2153-6. doi: 10.1021/ol050512o.
2
Enantio- and diastereoselective additions to aldehydes using the bifunctional reagent 2-(chloromethyl)-3-(tributylstannyl)propene: application to a synthesis of the C16-C27 segment of bryostatin 1.
J Org Chem. 2005 Apr 1;70(7):2543-50. doi: 10.1021/jo048308m.
3
Synthesis of the bryostatin 1 northern hemisphere (C1-C16) via desymmetrization by ketalization/ring-closing metathesis.
Org Lett. 2004 Oct 28;6(22):4045-8. doi: 10.1021/ol0483044.
4
Concise formal synthesis of the bryostatin southern hemisphere (C17-C27).
J Org Chem. 2004 Jun 25;69(13):4534-7. doi: 10.1021/jo0495081.
5
New, abridged pathway to Masamune's "southern hemisphere" intermediate for the total synthesis of bryostatin 7.
Org Lett. 2003 Feb 20;5(4):503-5. doi: 10.1021/ol027393m.
6
Synthesis of a simplified bryostatin C-ring analogue that binds to the CRD2 of human PKC-alpha and construction of a novel BC-analogue by an unusual Julia olefination process.
Org Lett. 2003 Feb 20;5(4):499-502. doi: 10.1021/ol027392u.
7
The practical synthesis of a novel and highly potent analogue of bryostatin.
J Am Chem Soc. 2002 Nov 20;124(46):13648-9. doi: 10.1021/ja027509+.
8
The chemistry and biology of the bryostatin antitumour macrolides.
Nat Prod Rep. 2002 Aug;19(4):413-53. doi: 10.1039/b009211h.
9
Pyran annulation: asymmetric synthesis of 2,6-disubstituted-4-methylene tetrahydropyrans.
Org Lett. 2002 Apr 4;4(7):1189-92. doi: 10.1021/ol025645d.
10
Chemistry and clinical biology of the bryostatins.
Bioorg Med Chem. 2000 Aug;8(8):1841-60. doi: 10.1016/s0968-0896(00)00150-4.
Zotero 插件