通过RcsCDB组氨酸-天冬氨酸磷酸化信号转导途径对大肠杆菌bdm（生物膜依赖性调节）基因进行渗透调节。
Osmotic regulation of the Escherichia coli bdm (biofilm-dependent modulation) gene by the RcsCDB His-Asp phosphorelay.
作者信息
Francez-Charlot Anne, Castanié-Cornet Marie-Pierre, Gutierrez Claude, Cam Kaymeuang
机构信息
Laboratoire de Microbiologie et de Génétique Moléculaire, Centre National de la Recherche Scientifique, 118 Route de Narbonne, 31062 Toulouse, France.
出版信息
J Bacteriol. 2005 Jun;187(11):3873-7. doi: 10.1128/JB.187.11.3873-3877.2005.
Abstract
The RcsCDB His-Asp phosphorelay is shown to positively regulate the bdm (biofilm-dependent modulation) and sra (stationary-phase-induced ribosome-associated protein) genes in Escherichia coli. The regulation is direct and requires an RcsB box next to the bdm -35 element. In addition, bdm is shown to be activated by osmotic shock in an Rcs-dependent way.
摘要
RcsCDB组氨酸-天冬氨酸磷酸化信号转导途径被证明可正向调控大肠杆菌中的bdm（生物膜依赖性调节）基因和sra（稳定期诱导的核糖体相关蛋白）基因。这种调控是直接的，并且需要在bdm基因的-35元件旁有一个RcsB框。此外，bdm基因被证明可通过Rcs依赖性方式被渗透压休克激活。
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