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广泛的发热检查在确定感染病因方面的阳性率较低。

Extensive fever workup produces low yield in determining infectious etiology.

作者信息

Schey Dana, Salom Emery M, Papadia Andrea, Penalver Manuel

机构信息

Department of Obstetrics and Gynecology, University of Miami, School of Medicine, Jackson Memorial Hospital, Fla 33136, USA.

出版信息

Am J Obstet Gynecol. 2005 May;192(5):1729-34. doi: 10.1016/j.ajog.2004.11.049.

Abstract

OBJECTIVE

The study was undertaken to evaluate the use of a fever workup in women undergoing benign gynecologic procedures.

STUDY DESIGN

A retrospective chart review was performed at Jackson Memorial Hospital between 1994 and 2000. Information was abstracted from hospital and clinic records. Fever criteria was defined as 1 temperature equal to or greater than 101.5, or 2 equal to or greater than 100.4, at least 4 hours apart within a 24-hour period. Patients undergoing additional intraoperative procedures leading to increased febrile morbidity were excluded. Data abstracted included patient demographics, procedure, complications, antibiotic use, and extent of fever workup. Statistical analysis used was 2-sample t tests, Wilcoxon rank test, chi2 test, and multivariate logistic regression. Alpha level = .05.

RESULTS

The charts of 505 patients were reviewed, and 147 patients met fever criteria. All patients underwent surgery for benign conditions, abdominal hysterectomy being the most common (90%). The study population was divided into 2 groups: the noninfectious group and infectious group. These groups were determined by wound infection, pelvic abscess, blood or urine culture, ultrasound, and chest roentgen. Both groups were found to be similar with respect to demographics, surgical procedures, and postoperative complications, with the exception of body mass index (28.4 vs 31.7) and length of hospital stay (3.9 vs 5.3). Results from fever workups included positive results blood cultures (9.7%), urine culture (18.8%), and chest roentgens (14%) in this study population. We found no association between positive urine analysis and urine culture. When comparing both groups, a statistically significant difference was found with regard to maximum temperature elevation, number of days febrile, and postoperative day of maximum temperature (P < .05).

CONCLUSION

The extensive fever workup was not frequently positive in this study population. Its use and cost-effectiveness should be questioned. Therefore, the fever workup should be tailored to the individual patient.

摘要

目的

本研究旨在评估对接受良性妇科手术的女性进行发热检查的应用情况。

研究设计

1994年至2000年间在杰克逊纪念医院进行了一项回顾性病历审查。信息从医院和诊所记录中提取。发热标准定义为:在24小时内,一次体温等于或高于101.5,或两次体温等于或高于100.4且间隔至少4小时。排除因额外的术中操作导致发热发病率增加的患者。提取的数据包括患者人口统计学信息、手术、并发症、抗生素使用情况以及发热检查的范围。所使用的统计分析方法包括两样本t检验、威尔科克森秩和检验、卡方检验以及多变量逻辑回归。显著性水平α = 0.05。

结果

审查了505例患者的病历,其中147例患者符合发热标准。所有患者均因良性疾病接受手术,最常见的是腹式子宫切除术(90%)。研究人群分为两组:非感染组和感染组。通过伤口感染、盆腔脓肿、血或尿培养、超声和胸部X线检查来确定分组。除体重指数(28.4对31.7)和住院时间(3.9天对5.3天)外,两组在人口统计学、手术操作和术后并发症方面相似。本研究人群发热检查的结果包括血培养阳性(9.7%)、尿培养阳性(18.8%)和胸部X线检查阳性(14%)。我们发现尿分析阳性与尿培养之间无关联。比较两组时,在最高体温升高、发热天数和最高体温出现的术后天数方面发现有统计学显著差异(P < 0.05)。

结论

在本研究人群中,广泛的发热检查结果阳性并不常见。其应用和成本效益值得质疑。因此,发热检查应根据个体患者进行调整。

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