Remplik P, Schukai O, Roemer F W, Schalm J, Fischer W, Bücklein W, Mott K, Bohndorf K
Klinik für Diagnostische Radiologie und Neuroradiologie, Klinikum Augsburg.
Rofo. 2005 Jun;177(6):842-8. doi: 10.1055/s-2005-858200.
To evaluate the influence of clinical information on the diagnostic validity of MRI in the detection of abacterial sacroiliitis. Evaluation of sensitivities, specificities, negative (NPV) and positive predictive values (PPV) for MRI with and without clinical information in comparison to a prior defined standard.
The results of routine MRI reports of 65 patients with the clinical suspicion of abacterial sacroiliitis referred by rheumatologists for MR assessment of the sacroiliac joints were retrospectively reviewed. These results were compared to the results of a blinded reading of the same examinations performed without any clinical information. The MRI protocol included T1-SE, STIR and T1-SE contrast-enhanced sequences with fat saturation. All patients were followed for at least four years. The standard of reference was defined by an experienced rheumatologist and included baseline and follow-up data (clinical, laboratory and imaging). Abacterial sacroiliitis was diagnosed in 19 patients.
Under routine clinical conditions, MRI revealed a sensitivity of 94.7 % and specificity of 97.8 %. A PPV of 94.7 % and a NPV of 97.8 % were achieved. Without clinical information, MRI revealed a sensitivity and specificity of 64 and 80 %, and a PPV of 49 % and a NPV of 86 %, respectively.
The additional knowledge of clinical information for the MR diagnosis of abacterial sacroiliitis increases its diagnostic value for the assessment of abacterial sacroiliitis.
评估临床信息对MRI诊断非细菌性骶髂关节炎有效性的影响。将有临床信息和无临床信息时MRI的敏感度、特异度、阴性预测值(NPV)和阳性预测值(PPV)与预先定义的标准进行比较。
回顾性分析65例临床怀疑非细菌性骶髂关节炎患者的常规MRI报告结果,这些患者由风湿病学家转诊来进行骶髂关节的MR评估。将这些结果与在无任何临床信息情况下对相同检查进行盲法解读的结果进行比较。MRI检查方案包括T1加权自旋回波序列(T1-SE)、短T1反转恢复序列(STIR)以及脂肪饱和T1加权自旋回波增强序列。所有患者均随访至少四年。参考标准由一位经验丰富的风湿病学家确定,包括基线和随访数据(临床、实验室和影像学)。19例患者被诊断为非细菌性骶髂关节炎。
在常规临床条件下,MRI的敏感度为94.7%,特异度为97.8%。阳性预测值为94.7%,阴性预测值为97.8%。在无临床信息时,MRI的敏感度和特异度分别为64%和80%,阳性预测值为49%,阴性预测值为86%。
临床信息对非细菌性骶髂关节炎MR诊断的补充知识提高了其对非细菌性骶髂关节炎评估的诊断价值。