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壁内血肿吸收后的穿透性主动脉溃疡。

Penetrating aortic ulcers after absorption of intramural hematoma.

作者信息

Aidala Enrico, Bardi Gianluca, Ohye Richard G

机构信息

Department of Cardiac Surgery, Ospedale S. Giovanni Battista (Molinette), 10126 Torino, Italy

出版信息

Tex Heart Inst J. 2005;32(1):81-4.

Abstract

We report a case of a type B aortic intramural hematoma, which rapidly expanded, with ulcer-like projections, after complete absorption of the hematoma. One month after the initial presentation, a new computed tomographic scan showed the appearance of a thin ulcer-like projection in the aortic wall. Three months later, after the patient reported a new episode of chest pain, a computed tomographic scan revealed 2 penetrating ulcers and rapid aortic dilation; the aortic hematoma had been completely absorbed. Urgent thoracic aortic replacement was undertaken. Three years postoperatively, the patient was asymptomatic, with no lesion or dilation of the aorta upon computed tomography. After an acute hematoma, the strength and structure of the aortic wall can alter rapidly. Damage and weakening of the aortic wall are caused mainly by infiltration of inflammatory cells, which have pronounced proteolytic and elastolytic activity. Due to the unstable nature of the lesion, optimal management remains controversial. In our patient, the inflammatory process led to the development of 2 aortic ulcers and aortic dilation within 3 months of the acute lesion, requiring urgent surgical intervention.

摘要

我们报告一例B型主动脉壁内血肿病例,该血肿在完全吸收后迅速扩大,并出现溃疡样凸起。初次就诊1个月后,新的计算机断层扫描显示主动脉壁出现薄的溃疡样凸起。3个月后,在患者报告新的胸痛发作后,计算机断层扫描显示2个穿透性溃疡和主动脉迅速扩张;主动脉血肿已完全吸收。遂进行了紧急胸主动脉置换术。术后3年,患者无症状,计算机断层扫描显示主动脉无病变或扩张。急性血肿后,主动脉壁的强度和结构可迅速改变。主动脉壁的损伤和弱化主要由具有明显蛋白水解和弹性蛋白水解活性的炎性细胞浸润引起。由于病变性质不稳定,最佳治疗方案仍存在争议。在我们的患者中,炎症过程在急性病变后3个月内导致了2个主动脉溃疡和主动脉扩张,需要紧急手术干预。

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本文引用的文献

1
Penetrating atherosclerotic ulcer of the descending thoracic aorta and arch.降主动脉和主动脉弓穿透性动脉粥样硬化溃疡
J Thorac Cardiovasc Surg. 2004 May;127(5):1393-9; discussion 1399-1401. doi: 10.1016/j.jtcvs.2003.11.050.

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