Pestalozzi B C, Jäger D, Knuth A
Klinik und Poliklinik für Onkologie, Universitätsspital Zürich, Schweiz.
Chirurg. 2005 Jun;76(6):570-2, 574. doi: 10.1007/s00104-005-1038-6.
Drug treatment of colorectal cancer has made impressive progress during the past 10 years. In addition to the traditional 5-fluorouracil, newer anticancer drugs are available including irinotecan and oxaliplatin. Monoclonal antibodies like bevacizumab and cetuximab have been integrated into modern treatment regimens. Based on randomized clinical trials we can formulate rational treatment strategies as outlined in this article.
在过去十年中，结直肠癌的药物治疗取得了令人瞩目的进展。除了传统的5-氟尿嘧啶外，还有包括伊立替康和奥沙利铂在内的新型抗癌药物。像贝伐单抗和西妥昔单抗这样的单克隆抗体已被纳入现代治疗方案。基于随机临床试验，我们可以制定本文所述的合理治疗策略。
