Kollmeier M, Brodhun M, Sliwka U, Sigusch H, Witte O W, Heide G
Klinik für Psychiatrie, Landeskrankenhaus Hildesheim.
Nervenarzt. 2006 Feb;77(2):187-8, 90-1. doi: 10.1007/s00115-005-1931-8.
Idiopathic giant cell myocarditis is a rare and frequently fatal inflammatory heart disease which leads to congestive heart failure or ventricular arrhythmias. It is often associated with other autoimmune disorders. We report a 39-year-old woman who first presented with diplopia and painful eye movements, the typical clinical picture of orbital myositis. Shortly afterwards, she developed rapidly progressive congestive heart failure due to giant cell myocarditis, which took a fatal course within some weeks. Autopsy confirmed both disorders. This case report underlines the importance of early and repeated monitoring of cardiac function, if orbital myositis is suspected, in order to consider cardiac transplantation, the only efficacious treatment of giant cell myocarditis, in time.
特发性巨细胞性心肌炎是一种罕见且常致命的炎症性心脏病,可导致充血性心力衰竭或室性心律失常。它常与其他自身免疫性疾病相关。我们报告一名39岁女性,最初表现为复视和眼球运动疼痛,这是眼眶肌炎的典型临床表现。此后不久,她因巨细胞性心肌炎迅速发展为进行性充血性心力衰竭,并在数周内病情恶化死亡。尸检证实了这两种疾病。本病例报告强调,如果怀疑眼眶肌炎,早期和反复监测心脏功能的重要性,以便及时考虑心脏移植,这是巨细胞性心肌炎唯一有效的治疗方法。