Zhou Hui, Huang Yinxi, Hoshi Tomonori, Kashiwagi Yoshitomo, Anzai Jun-Ichi, Li Genxi
Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing 210093, PR China.
Anal Bioanal Chem. 2005 Jun;382(4):1196-201. doi: 10.1007/s00216-005-3241-1. Epub 2005 May 20.
Sinapine (O-sinapoyl choline) is a crucial component, with much medicinal value, of many dietary and medicinal plants. It has been found that sinapine gives an electrochemical response at a pyrolytic graphite electrode. The electrochemical properties of sinapine have been investigated. The peak current in the cyclic voltammogram is linear in the concentration range 1.9 x 10(-6)-2.5 x 10(-4) mol L(-1) and the limit of detection is 9.9 x 10(-7) mol L(-1). These properties can be applied to the determination of sinapine in extracts from three kinds of medicinal plant. The electrochemical method reported here is highly selective, sensitive, and stable.
芥子碱（O-芥子酰胆碱）是许多食用和药用植物的关键成分，具有很高的药用价值。研究发现，芥子碱在热解石墨电极上会产生电化学响应。已对芥子碱的电化学性质进行了研究。循环伏安图中的峰值电流在1.9×10⁻⁶ - 2.5×10⁻⁴ mol L⁻¹浓度范围内呈线性，检测限为9.9×10⁻⁷ mol L⁻¹。这些性质可应用于三种药用植物提取物中芥子碱的测定。本文报道的电化学方法具有高选择性、高灵敏度和稳定性。
