一名特发性血小板减少性紫癜患者的肾移植

Hwang Eun Mi, Woo Hyun Young, Choi Beom Soon, Yang Chul Woo, Kim Yong Soo, Moon In Sung, Bang Byung Kee

Department of Internal Medicine, Kangnam St. Mary's Hospital, The Catholic University of Korea College of Medicine, Seoul, Korea.

Korean J Intern Med. 2005 Mar;20(1):92-5. doi: 10.3904/kjim.2005.20.1.92.

The combination of idiopathic thrombocytopenic purpura (ITP) and chronic renal failure (CRF) is uncommon. This report highlights a case of renal transplantation in a patient with ITP. A 35-year-old man with ITP was admitted with uremic symptoms. A renal transplant and splenectomy was simultaneously performed. A prophylactic pneumococcous vaccination was performed and intravenous immunoglobulin (1 g/kg) was administered before and after the operation. The patient's platelet count increased gradually after the splenectomy. During a two-year follow up period, the graft function was well maintained. Renal transplantation in a patient with ITP is recommended with a well-designed strategy to prevent potential complications.

特发性血小板减少性紫癜（ITP）与慢性肾衰竭（CRF）并存的情况并不常见。本报告重点介绍了1例ITP患者的肾移植病例。一名患有ITP的35岁男性因出现尿毒症症状入院。同时进行了肾移植和脾切除术。进行了预防性肺炎球菌疫苗接种，并在手术前后给予静脉注射免疫球蛋白（1 g/kg）。脾切除术后患者的血小板计数逐渐升高。在两年的随访期内，移植肾功能维持良好。建议对ITP患者进行肾移植，并制定精心设计的策略以预防潜在并发症。