Luni Yasmin, Munim Shama, Qureshi Rahat, Tareen Abdul Latif
Department of Obstetrics & Gynaecology, The Aga Khan University Hospital, Karachi, Pakistan.
J Coll Physicians Surg Pak. 2005 May;15(5):270-2.
To determine the frequency of bacterial vaginosis (BV) in women with vaginal discharge, and to compare different diagnostic tests for its diagnosis.
Cross-sectional study.
The Aga Khan University Hospital from June 1998 to May 2000.
All women attending the Obstetrics and Gynecology clinics at The Aga Khan University Hospital, with the complaints of vaginal discharge, were examined with the help of a speculum. The vaginal pH was measured, samples for bacterial cultures were obtained. A slide was prepared for the gram's stain and Whiff-test was also performed. BV was diagnosed, when the vaginal discharge fulfilled at least three of the composite clinical criteria (Amsel's criteria), a standard method for the diagnosis of bacterial vaginosis: homogenous (pasty) discharge, pH more than 4.5, positive Whiff-test and the presence of clue cells.
The frequency of BV was observed to be 16.1% . The culture for Gardnerella vaginalis was compared with the composite clinical criteria. The sensitivity, specificity, positive and negative predictive values of the culture, calculated for the diagnosis of BV were 93.8%, 70%, 37.7% and 98% respectively.
The use of laboratory tests in conjunction with clinical findings is necessary for diagnosis of BV. The composite clinical criteria for the diagnosis of BV are rapid, reliable and inexpensive method.
确定有阴道分泌物的女性中细菌性阴道病（BV）的发生率，并比较其不同诊断测试方法。
横断面研究。
1998年6月至2000年5月在阿迦汗大学医院。
所有到阿迦汗大学医院妇产科门诊就诊、主诉有阴道分泌物的女性，均在阴道窥器辅助下进行检查。测量阴道pH值，采集细菌培养样本。制备革兰氏染色玻片并进行胺试验。当阴道分泌物符合至少三项综合临床标准（阿姆斯勒标准）时，诊断为BV，这是诊断细菌性阴道病的标准方法：均质（糊状）分泌物、pH值大于4.5、胺试验阳性及出现线索细胞。
观察到BV的发生率为16.1%。将阴道加德纳菌培养结果与综合临床标准进行比较。计算得出，用于诊断BV的培养方法的敏感性、特异性、阳性预测值和阴性预测值分别为93.8%、70%、37.7%和98%。
诊断BV需要结合实验室检查和临床发现。BV诊断的综合临床标准是一种快速、可靠且廉价的方法。
