革兰氏染色与巴氏涂片法在细菌性阴道病诊断中的比较。
Comparison of Gram stain and Pap smear procedures in the diagnosis of bacterial vaginosis.
作者信息
Vardar Enver, Maral Izzet, Inal Murat, Ozgüder Ozgül, Tasli Funda, Postaci Hakan
机构信息
Pathology Department, SSK Izmir Training Hospital, Turkey.
出版信息
Infect Dis Obstet Gynecol. 2002;10(4):203-7. doi: 10.1155/S1064744902000236.
OBJECTIVE
The purpose of this study was to examine the characteristics of Gram stain versus Pap smear in diagnosis of bacterial vaginosis (BV).
METHODS
One-thousand and sixty women were enrolled in this study. All cases with symptoms of BV were determined by Amsel's criteria, which were accepted as the gold standard for diagnosis of BV. Pap smear and Gram stain evaluations were compared according to Amsel's criteria, without viewing the clinical results of the patients. Gram stain and Pap smear results were determined as negative or positive according to Amsel's criteria. Sensitivity, specifity and positive predictive values were calculated.
RESULTS
After accepting the cases that were diagnosed as BV according to Amsel's criteria as reference cases, the sensitivity of the Gram stain method was calculated as 97% and the sensitivity of the Pap smear method as 93%. Similar specificity rates were obtained with both methods in diagnosis of BV related to the clinical results. There were no statistically significant differences in diagnosis of BV between these two groups.
CONCLUSION
If Amsel's criteria are accepted as the gold standard for diagnosis of BV, Gram stain and Pap smear methods will give similar results in diagnosis.
目的
本研究旨在探讨革兰氏染色与巴氏涂片在细菌性阴道病（BV）诊断中的特点。
方法
1060名女性参与了本研究。所有有BV症状的病例均根据阿姆斯勒标准进行判定，该标准被视为BV诊断的金标准。根据阿姆斯勒标准比较巴氏涂片和革兰氏染色评估结果，不考虑患者的临床结果。革兰氏染色和巴氏涂片结果根据阿姆斯勒标准判定为阴性或阳性。计算敏感性、特异性和阳性预测值。
结果
将根据阿姆斯勒标准诊断为BV的病例作为参照病例后，革兰氏染色法的敏感性计算为97%，巴氏涂片法的敏感性为93%。在与临床结果相关的BV诊断中，两种方法获得了相似的特异性率。两组在BV诊断方面无统计学显著差异。
结论
如果将阿姆斯勒标准作为BV诊断的金标准，革兰氏染色和巴氏涂片法在诊断中会得出相似的结果。
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