Hussain Altaf, Ahmad Farooq, Khawar Anjum, Bangash Wajahat, Khan M Yasir
ENT Unit, PIMS, Islamabad.
J Coll Physicians Surg Pak. 2005 May;15(5):273-5.
To determine the relationship of lymph node metastasis with smoking in T1 and T2 staged squamous cell carcinoma (SCC) of tongue.
An analytical study.
ENT Department of Pakistan Institute of Medical Sciences, Islamabad, from 1st January 2001 to 31st December 2002.
A total of 60 patients of T1 and T2 of SCC of oral tongue were selected. These patients were divided into two groups on the basis of history of smoking. Also these patients were clinically examined for lymph node metastasis and FNAC done for the confirmation of diagnosis. Odds ratio (OR) and p-value were statistically determined to asses the association between lymph node metastasis and smoking.
The odds ratio for patients with history of smoking to develop lymph node metastasis was 1.896 but association was statistically insignificant (p = 0.24).
This study indicates that although smoking increases the risk for lymph node metastasis but the association is insignificant in T1 and T2 staged SCC of tongue.
确定舌部T1和T2期鳞状细胞癌（SCC）中淋巴结转移与吸烟的关系。
一项分析性研究。
2001年1月1日至2002年12月31日，位于伊斯兰堡的巴基斯坦医学科学研究所耳鼻喉科。
共选取60例口腔舌部SCC的T1和T2期患者。这些患者根据吸烟史分为两组。对这些患者进行临床淋巴结转移检查，并进行细针穿刺抽吸活检（FNAC）以确诊。通过统计学方法确定优势比（OR）和p值，以评估淋巴结转移与吸烟之间的关联。
有吸烟史的患者发生淋巴结转移的优势比为1.896，但该关联在统计学上无显著意义（p = 0.24）。
本研究表明，虽然吸烟会增加淋巴结转移的风险，但在舌部T1和T2期SCC中，这种关联并不显著。
