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小儿年龄组血液透析的急性并发症

Acute complications of haemodialysis in paediatric age group.

作者信息

Hafeez Farkhanda

机构信息

Department of Paediatric Nephrology, The Children's Hospital & Institute of Child Health,

出版信息

J Coll Physicians Surg Pak. 2005 May;15(5):280-3.

Abstract

OBJECTIVE

To assess acute complications of haemodialysis in patients with end-stage renal disease (ESRD).

DESIGN

Observational study.

PLACE AND DURATION OF STUDY

The Nephrology Department of The Children's Hospital and Institute of Child Health, Lahore over a period of 2 years (January 2001-December 2002).

PATIENTS AND METHODS

The children in age group of 6-14 years, suffering from end-stage renal disease (ESRD), were provided renal replacement therapy in the form of haemodialysis mostly twice a week and were observed for the complications of the procedure.

RESULTS

A total 519 haemodialysis were performed on 25 patients. The mean age was 11.06 years and weight was 26.8 kg. The clinical problems observed were hypertension in 40.46%, hypotension 3.4%, chest pain 4.04%, headache 13.87%, vomiting 1.73%, gastrointestinal bleeding 1.92%, muscle cramps 8.6% and convulsions 0.57% of sessions. Hypokalemia was main electrolyte disturbance seen during 8%, while fever with rigors and chills in 4.02% of sessions. Minor bleeding from subclavian catheter was seen during 2.89% of sessions while thrombosis, infection and accidental dislodgment in 0.77%, 12.50% and 0.57% of sessions respectively. Technical problems like clotting in dialyzer during 0.95% and failure of ultra-violet control module was seen in 3.42% of sessions.

CONCLUSION

Haemodialysis, a life saving treatment modality, is not without risk of complications. Hypertension, headache, muscle cramps and catheter infections were the most commonly encountered complications in this series.

摘要

目的

评估终末期肾病(ESRD)患者血液透析的急性并发症。

设计

观察性研究。

研究地点及时间

拉合尔儿童医院及儿童健康研究所肾病科,为期2年(2001年1月至2002年12月)。

患者及方法

6至14岁患有终末期肾病(ESRD)的儿童,接受每周大多两次的血液透析形式的肾脏替代治疗,并观察该治疗过程中的并发症。

结果

对25例患者共进行了519次血液透析。平均年龄为11.06岁,体重为26.8千克。观察到的临床问题包括:40.46%的透析过程出现高血压,3.4%出现低血压,4.04%出现胸痛,13.87%出现头痛,1.73%出现呕吐,1.92%出现胃肠道出血,8.6%出现肌肉痉挛,0.57%出现惊厥。低血钾是8%的透析过程中出现的主要电解质紊乱,4.02%的透析过程出现寒战高热。2.89%的透析过程出现锁骨下导管轻微出血,血栓形成、感染和意外拔管分别占透析过程的0.77%、12.50%和0.57%。0.95%的透析过程出现透析器凝血等技术问题,3.42%的透析过程出现紫外线控制模块故障。

结论

血液透析作为一种挽救生命的治疗方式,并非没有并发症风险。高血压、头痛、肌肉痉挛和导管感染是本系列中最常见的并发症。

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