Hafeez Farkhanda
Department of Paediatric Nephrology, The Children's Hospital & Institute of Child Health,
J Coll Physicians Surg Pak. 2005 May;15(5):280-3.
To assess acute complications of haemodialysis in patients with end-stage renal disease (ESRD).
Observational study.
The Nephrology Department of The Children's Hospital and Institute of Child Health, Lahore over a period of 2 years (January 2001-December 2002).
The children in age group of 6-14 years, suffering from end-stage renal disease (ESRD), were provided renal replacement therapy in the form of haemodialysis mostly twice a week and were observed for the complications of the procedure.
A total 519 haemodialysis were performed on 25 patients. The mean age was 11.06 years and weight was 26.8 kg. The clinical problems observed were hypertension in 40.46%, hypotension 3.4%, chest pain 4.04%, headache 13.87%, vomiting 1.73%, gastrointestinal bleeding 1.92%, muscle cramps 8.6% and convulsions 0.57% of sessions. Hypokalemia was main electrolyte disturbance seen during 8%, while fever with rigors and chills in 4.02% of sessions. Minor bleeding from subclavian catheter was seen during 2.89% of sessions while thrombosis, infection and accidental dislodgment in 0.77%, 12.50% and 0.57% of sessions respectively. Technical problems like clotting in dialyzer during 0.95% and failure of ultra-violet control module was seen in 3.42% of sessions.
Haemodialysis, a life saving treatment modality, is not without risk of complications. Hypertension, headache, muscle cramps and catheter infections were the most commonly encountered complications in this series.
评估终末期肾病(ESRD)患者血液透析的急性并发症。
观察性研究。
拉合尔儿童医院及儿童健康研究所肾病科,为期2年(2001年1月至2002年12月)。
6至14岁患有终末期肾病(ESRD)的儿童,接受每周大多两次的血液透析形式的肾脏替代治疗,并观察该治疗过程中的并发症。
对25例患者共进行了519次血液透析。平均年龄为11.06岁,体重为26.8千克。观察到的临床问题包括:40.46%的透析过程出现高血压,3.4%出现低血压,4.04%出现胸痛,13.87%出现头痛,1.73%出现呕吐,1.92%出现胃肠道出血,8.6%出现肌肉痉挛,0.57%出现惊厥。低血钾是8%的透析过程中出现的主要电解质紊乱,4.02%的透析过程出现寒战高热。2.89%的透析过程出现锁骨下导管轻微出血,血栓形成、感染和意外拔管分别占透析过程的0.77%、12.50%和0.57%。0.95%的透析过程出现透析器凝血等技术问题,3.42%的透析过程出现紫外线控制模块故障。
血液透析作为一种挽救生命的治疗方式,并非没有并发症风险。高血压、头痛、肌肉痉挛和导管感染是本系列中最常见的并发症。