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带状疱疹后神经痛的治疗。

Treatment of postherpetic neuralgia.

作者信息

Nurmikko T J, Haanpää M

机构信息

Pain Research Institute, Division of Neurological Science, School of Clinical Science, University of Liverpool, Lower Lane, Liverpool L9 7AL, United Kingdom.

出版信息

Curr Pain Headache Rep. 2005 Jun;9(3):161-7. doi: 10.1007/s11916-005-0057-9.

DOI:10.1007/s11916-005-0057-9
PMID:15907253
Abstract

Postherpetic neuralgia (PHN) remains one of the most troublesome common chronic neuropathic pain conditions. Many controlled trials have been published showing good efficacy and reasonable tolerability. These include gabapentinoids, opioids, tricyclic antidepressants, and topical lidocaine and capsaicin. Combination therapies are possible, but have not been proven, and long-term follow-up is limited. Only few case series exist for surgical and other invasive therapies and their role remains uncertain.

摘要

带状疱疹后神经痛(PHN)仍然是最棘手的常见慢性神经性疼痛病症之一。许多对照试验已经发表,显示出良好的疗效和合理的耐受性。这些药物包括加巴喷丁类药物、阿片类药物、三环类抗抑郁药以及局部用利多卡因和辣椒素。联合治疗是可行的,但尚未得到证实,且长期随访有限。关于手术和其他侵入性治疗的病例系列很少,其作用仍不确定。

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本文引用的文献

1
Morphine, gabapentin, or their combination for neuropathic pain.吗啡、加巴喷丁或其联合用药治疗神经性疼痛。
N Engl J Med. 2005 Mar 31;352(13):1324-34. doi: 10.1056/NEJMoa042580.
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Treatment of postherpetic neuralgia: a review of therapeutic options.带状疱疹后神经痛的治疗:治疗选择综述
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实践参数:带状疱疹后神经痛的治疗:美国神经病学学会质量标准小组委员会的循证报告
Neurology. 2004 Sep 28;63(6):959-65. doi: 10.1212/01.wnl.0000140708.62856.72.
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Neuraxial and sympathetic blocks in herpes zoster and postherpetic neuralgia: an appraisal of current evidence.带状疱疹及疱疹后神经痛中的神经轴索阻滞和交感神经阻滞:当前证据评估
Reg Anesth Pain Med. 2004 Sep-Oct;29(5):454-61. doi: 10.1016/j.rapm.2004.04.010.
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Peripheral stimulation for treatment of trigeminal postherpetic neuralgia and trigeminal posttraumatic neuropathic pain: a pilot study.周围神经刺激治疗三叉神经带状疱疹后神经痛和三叉神经创伤后神经性疼痛:一项初步研究。
Neurosurgery. 2004 Jul;55(1):135-41; discussion 141-2.
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Risk factors for postherpetic neuralgia in patients with herpes zoster.带状疱疹患者发生带状疱疹后神经痛的危险因素。
Neurology. 2004 May 11;62(9):1545-51. doi: 10.1212/01.wnl.0000123261.00004.29.
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Lidocaine patch 5% reduces pain intensity and interference with quality of life in patients with postherpetic neuralgia: an effectiveness trial.5%利多卡因贴剂可减轻带状疱疹后神经痛患者的疼痛强度并减少对生活质量的干扰:一项有效性试验。
Pain Med. 2002 Dec;3(4):324-32. doi: 10.1046/j.1526-4637.2002.02050.x.
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Pregabalin reduces pain and improves sleep and mood disturbances in patients with post-herpetic neuralgia: results of a randomised, placebo-controlled clinical trial.普瑞巴林可减轻带状疱疹后神经痛患者的疼痛,并改善睡眠和情绪障碍:一项随机、安慰剂对照临床试验的结果。
Pain. 2004 May;109(1-2):26-35. doi: 10.1016/j.pain.2004.01.001.
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Chronic noncancer pain and the long term utility of opioids.慢性非癌性疼痛与阿片类药物的长期效用
Pain Res Manag. 2004 Spring;9(1):19-24. doi: 10.1155/2004/304094.
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Interventions to prevent postherpetic neuralgia: cutaneous and percutaneous techniques.预防带状疱疹后神经痛的干预措施:皮肤和经皮技术
Pain. 2004 Feb;107(3):202-206. doi: 10.1016/j.pain.2003.10.021.