Iqbal Sofia Inez, Mørch Lina Steinrud, Rosenzweig Mary, Dela Flemming
Depart of Medical Physiology/Copenhagen Muscle Research Centre, Section of Pathophysiology, The Panum Institute, University of Copenhagen, Copenhagen, Denmark.
J Clin Densitom. 2005 Summer;8(2):178-82. doi: 10.1385/jcd:8:2:178.
The incidence of osteoporosis is increasing and the general practitioner is integral to identifying these patients. It is, therefore, of interest to characterize the referral pattern of patients scheduled for determination of bone density by means of dual-energy X-ray absorptiometry scanning. Altogether, 1551 scans from first-time referred women were analyzed with respect to normal bone mineral density (BMD), osteopenia, and osteoporosis as the outcome, and the results were compared with age and body mass index (BMI). Using multiple regression analysis, risk estimates for osteoporosis were calculated with respect to patient characteristics. Only 21% of the referred patients had osteoporosis and 34% had osteopenia. Of these, 24% had osteopenia and a Z-score below -1. Half of the referred patients were women less than 60 yr with a markedly low risk of osteoporosis. A BMI less than 20 kg/m(2) increased the predictive value considerably. A low BMI is a good indicator for referral of women less than 60 yr for measurements of bone density. Forty-five percent of the referred women from general practitioners had a normal BMD.
骨质疏松症的发病率正在上升，全科医生对于识别这些患者至关重要。因此，了解通过双能X线吸收法扫描来测定骨密度的患者转诊模式很有意义。总共分析了1551例首次转诊女性的扫描结果，将正常骨矿物质密度（BMD）、骨质减少和骨质疏松作为结果，并将结果与年龄和体重指数（BMI）进行比较。使用多元回归分析，根据患者特征计算骨质疏松症的风险估计值。仅21%的转诊患者患有骨质疏松症，34%患有骨质减少。其中，24%的患者骨质减少且Z值低于-1。一半的转诊患者为60岁以下女性，骨质疏松风险极低。BMI低于20kg/m²会显著增加预测值。低BMI是60岁以下女性转诊进行骨密度测量的良好指标。45%来自全科医生转诊的女性骨密度正常。
