Farag R, Schulak J A, Abdul-Karim F W, Wasman J K
Department of Pathology, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, Cleveland, OH 44106, USA.
Clin Nephrol. 2005 May;63(5):408-12. doi: 10.5414/cnp63408.
Angiosarcoma in the setting of immunosuppressed renal transplant recipients is exceedingly rare. In this report, we describe the occurrence of angiosarcoma arising at an arteriovenous fistula site of a 39-year-old renal transplant recipient that clinically mimicked a thrombosed aneurysm. These tumors are histologically high-grade and clinically aggressive malignancies. They have a predilection for arteriovenous fistula sites. The literature on this uncommon entity is reviewed and possible histogenesis is discussed.
免疫抑制的肾移植受者发生血管肉瘤极为罕见。在本报告中,我们描述了一名39岁肾移植受者动静脉瘘部位发生的血管肉瘤,临床上酷似血栓形成的动脉瘤。这些肿瘤在组织学上为高级别,临床上具有侵袭性。它们好发于动静脉瘘部位。本文回顾了关于这一罕见实体的文献并讨论了可能的组织发生。