Teddy P, Jamous A, Gardner B, Wang D, Silver J
National Spinal Injuries Centre, Stoke Mandeville Hospital, Aylesbury, Bucks, UK.
Br J Neurosurg. 1992;6(2):115-8. doi: 10.3109/02688699209002912.
The medical records of 46 consecutive patients who have had intrathecal Baclofen drug delivery systems implanted in the National Spinal Injuries Centre, the Paddocks Hospital Spinal Unit, Princes Risborough, Lodge Moor Hospital Spinal Unit, Sheffield, the Northern Regional Spinal Injuries Unit, Hexham and The Radcliffe Infirmary, Oxford, were reviewed. Patients were contacted to describe their views on the treatment. The complications of the treatment are described. Some, such as overdose and meningitis are particularly hazardous. Others, in particular pump tubing revisions, are more of an inconvenience and time consuming for the patient and physician. If the serious risks of this valuable treatment are to be minimized and the therapy applied most effectively than a well co-ordinated team is essential, involving in particular the physician responsible for the initial assessment and follow-up of the patient and an experienced surgeon. It is recommended that only a small number of centres in the UK undertake these implants.
回顾了在国家脊髓损伤中心、帕多克斯医院脊柱科(位于王子里斯伯勒)、洛奇摩尔医院脊柱科(位于谢菲尔德)、北部地区脊髓损伤科(位于赫克瑟姆)以及牛津拉德克利夫医院,连续46例接受鞘内巴氯芬药物输送系统植入的患者的病历。与患者取得联系,以了解他们对该治疗的看法。描述了该治疗的并发症。其中一些,如用药过量和脑膜炎,特别危险。其他一些,尤其是泵管的更换,对患者和医生来说更多的是不便和耗时。若要将这种有价值的治疗的严重风险降至最低,并最有效地应用该疗法,那么一个协调良好的团队至关重要,尤其要包括负责患者初始评估和随访的医生以及一位经验丰富的外科医生。建议英国仅少数几个中心开展这些植入手术。