Bowman层决定角膜的生物力学特性吗？
Does Bowman's layer determine the biomechanical properties of the cornea?
作者信息
Seiler T, Matallana M, Sendler S, Bende T
机构信息
Universitäts-Augenklinik im Klinikum Charlottenburg, Freie Universität Berlin, Germany.
出版信息
Refract Corneal Surg. 1992 Mar-Apr;8(2):139-42.
BACKGROUND
Bowman's layer is believed to be the stabilizing element of corneal curvature due to its assumed mechanical stiffness.
METHODS
Uniaxial stress-strain analysis was performed in paired corneal strips to compare the contribution from Bowman's layer. Two central strips were taken from each cornea and Bowman's layer was removed from one of them with the excimer laser.
RESULTS
Pairwise comparison yielded no statistical difference in elastic or viscoelastic properties according to presence or absence of Bowman's layer. At a strain of 2%, the stress was measured to be (5.06 +/- 2.01) x 10(3) N/m2 with Bowman's layer and (4.72 +/- 1.3) x 10(3) N/m2 without Bowman's layer. Also, the two relaxation times did not differ significantly.
CONCLUSIONS
These findings imply that Bowman's layer does not contribute significantly to mechanical stability within the cornea.
背景
由于Bowman层假定的机械刚度，它被认为是角膜曲率的稳定因素。
方法
对成对的角膜条进行单轴应力-应变分析，以比较Bowman层的贡献。从每个角膜取两条中央条带，其中一条用准分子激光去除Bowman层。
结果
根据Bowman层的有无，成对比较在弹性或粘弹性特性方面未产生统计学差异。在2%的应变下，有Bowman层时测得的应力为(5.06±2.01)×10(3) N/m2，无Bowman层时为(4.72±1.3)×10(3) N/m2。此外，两个弛豫时间没有显著差异。
结论
这些发现表明Bowman层对角膜内的机械稳定性贡献不大。
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