Verhaeghe B J, Van Bocxlaer J F, De Leenheer A P
Laboratoria voor Medische Biochemie en Klinische Analyse, Rijksuniversiteit Gent, Belgium.
Biol Mass Spectrom. 1992 Jan;21(1):27-32. doi: 10.1002/bms.1200210107.
Organic acid profiles were routinely analysed for two patients suffering from a massive 3-hydroxydicarboxyluria and five patients suffering from ketoaciduria. The identification of the urinary, saturated and unsaturated 3-hydroxydicarboxylic acids as their trimethylsilyl derivatives was performed with electron impact and positive chemical ionization gas chromatography/mass spectrometry. Additionally, their methylene units have been determined on SE-52 and OV-1701 types of stationary phases.
对两名患有大量3-羟基二羧酸尿症的患者和五名患有酮酸尿症的患者常规分析了有机酸谱。通过电子轰击和正化学电离气相色谱/质谱法对尿中饱和和不饱和3-羟基二羧酸的三甲基硅烷基衍生物进行鉴定。此外，在SE-52和OV-1701类型的固定相上测定了它们的亚甲基单元。
