Alabdulkarim Maher, Bissada Nabil, Al-Zahrani Mohammad, Ficara Anthony, Siegel Burton
Ministry of Health, Riyadh, Saudi Arabia.
J Int Acad Periodontol. 2005 Apr;7(2):34-8.
Obesity was found to be significantly associated with periodontal disease prevalence as measured by probing depth and clinical attachment loss. The aim of this study was to examine if obesity correlates with chronic periodontitis as diagnosed by radiographic alveolar bone loss.
Four hundred subjects > or =18 years old were included; 200 with body mass index (BMI) > or =30 kg/m2 (obese) and 200 with BMI < 25 kg/m2 (non-obese). Alveolar bone loss was determined from full mouth radiographs for each subject. Logistic regression models were used to estimate the association of obesity and periodontitis.
Obesity was found to be significantly associated with periodontitis in the uni-variate regression analysis (OR = 2.37, 95% CI, 1.55-3.63). After adjusting for age, gender, smoking, employment, diabetes, marital status, and number of teeth present, obese subjects were found to be 1.86 times more likely to have periodontitis (95% CI, 0.99-3.51) than non-obese ones. When the sample was stratified based on age, the multivariate association was statistically significant among individuals < 40 years of age (OR = 2.67, 95% CI, 1.09-6.58) while among individuals > or = 40 years of age the association was statistically insignificant (OR = 1.06, 95% CI, 0.57-1.95). Stratifying the sample based on gender and smoking status revealed a stronger association among females than males (OR = 3.14 vs. 1.95) and among non-smokers than smokers (OR = 3.36 vs. 2.22).
Obesity is associated with increased prevalence of periodontitis as measured by radiographic alveolar bone loss, especially among younger individuals. Prevention and management of obesity may be considered to promote better systemic and periodontal health.
研究发现，通过牙周探诊深度和临床附着丧失测量，肥胖与牙周病患病率显著相关。本研究旨在探讨肥胖与影像学诊断的牙槽骨丧失所确诊的慢性牙周炎之间是否存在关联。
纳入400名年龄≥18岁的受试者；其中200名体重指数（BMI）≥30kg/m²（肥胖组），200名BMI＜25kg/m²（非肥胖组）。通过每位受试者的全口X光片确定牙槽骨丧失情况。采用逻辑回归模型评估肥胖与牙周炎之间的关联。
单变量回归分析发现肥胖与牙周炎显著相关（比值比[OR]=2.37，95%置信区间[CI]，1.55 - 3.63）。在对年龄、性别、吸烟、就业情况、糖尿病、婚姻状况和现存牙齿数量进行校正后，发现肥胖受试者患牙周炎的可能性是非肥胖受试者的1.86倍（95%CI，0.99 - 3.51）。当样本按年龄分层时，40岁以下个体的多变量关联具有统计学意义（OR = 2.67，95%CI，1.09 - 6.58），而40岁及以上个体的关联无统计学意义（OR = 1.06，95%CI，0.57 - 1.95）。按性别和吸烟状况对样本进行分层后发现，女性中的关联比男性更强（OR = 3.14对1.95），非吸烟者中的关联比吸烟者更强（OR = 3.36对2.22）。
通过影像学牙槽骨丧失测量，肥胖与牙周炎患病率增加相关，尤其是在年轻个体中。可考虑预防和管理肥胖以促进更好的全身和牙周健康。
