Kolz Angela C, Ong Say Kee, Moorman T B
Department of Civil, Construction and Environmental Engineering, Iowa State University, Ames, Iowa 50011, United States.
Chemosphere. 2005 Jul;60(2):284-9. doi: 10.1016/j.chemosphere.2005.02.094. Epub 2005 Apr 26.
Sorption of tylosin was conducted on manure solids (<2 mm) and colloidal materials (<1.2 microm) collected from open (OL) and covered (CL) anaerobic swine manure lagoons. The aqueous concentration of tylosin in the sorption studies bracket the levels expected in lagoons, between 1 mgl(-1) and 30 mgl(-1). Sorption isotherms were found to be slightly non-linear for 2 mm solids, with Freundlich distribution coefficients (K(f)) of 39.4 with n=1.32 for CL slurry and 99.5 with n=1.02 for OL. These values are comparable to those reported for loam soils, but higher than those reported for sandy or clay soils and lower than those reported for fresh manure. Normalization of K(d) to the organic carbon content of the solids gave K(oc) values of 570 lkg(-1) and 818 lkg(-1), for CL and OL solids, respectively. The K(d) and K(f) values were not significantly different between colloids and 2 mm solids in OL slurry, but were significantly different in CL due to the non-linearity of the colloid isotherm. Based on the K(d) values obtained and comparing the K(d) values of other antibiotics, tylosin is strongly sorbed to manure, and would be more mobile than tetracyclines, but less mobile than sulfonamides, olaquindox, and chloramphenicol. However, tylosin mobility may be facilitated through transport with colloidal manure materials.
对从开放式（OL）和封闭式（CL）厌氧猪粪泻湖收集的粪便固体（<2毫米）和胶体物质（<1.2微米）进行了泰乐菌素的吸附研究。吸附研究中泰乐菌素的水溶液浓度处于泻湖预期水平范围内，介于1毫克/升和30毫克/升之间。发现2毫米固体的吸附等温线略呈非线性，CL泥浆的弗伦德利希分配系数（K(f)）为39.4，n = 1.32；OL的为99.5，n = 1.02。这些值与壤土报道的值相当，但高于砂土或黏土报道的值，低于新鲜粪便报道的值。将K(d)归一化至固体的有机碳含量后，CL和OL固体的K(oc)值分别为570升/千克和818升/千克。OL泥浆中胶体和2毫米固体之间的K(d)和K(f)值无显著差异，但由于胶体等温线的非线性，CL中的这些值存在显著差异。基于获得的K(d)值并与其他抗生素的K(d)值比较，泰乐菌素强烈吸附于粪便，其迁移性比四环素高，但比磺胺类、喹乙醇和氯霉素低。然而，泰乐菌素的迁移可能通过与胶体粪便物质一起运输而得到促进。
