Pagniez H, Berche P
Service de microbiologie, hôpital Necker-Enfants-malades, 149, rue de Sèvres, 75743 Paris cedex 15, France.
Med Mal Infect. 2005 Apr;35(4):186-91. doi: 10.1016/j.medmal.2005.03.008.
Shewanella putrefaciens and Shewanella algae are Gram negative, nonfermentative and oxidative bacilli whose the main phenotypic feature is the production of hydrogen sulfide gas. Widespread in the environment, both S. putrefaciens and S. algae species are rare human bacteria although they are reported with increasing frequency as a cause of opportunistic infection in humans, such as skin and soft tissue infections and bacteremia. Chronic infections of the lower limbs and liver disease have been identified as risk factors for bloodstream infection, with a faster course and a poorer prognosis in the last case. S. algae appears to be more virulent than S. putrefaciens. Most human S. putrefaciens strains are isolated from bacterial flora, which puts to question its clinical significance. Molecular biology must be used for an adequate identification because S. algae can easily be mistaken for S. putrefaciens with usual tests.
腐败希瓦氏菌和海藻希瓦氏菌是革兰氏阴性、非发酵且需氧的杆菌,其主要表型特征是产生硫化氢气体。这两种菌在环境中广泛存在,虽然作为人类机会性感染(如皮肤和软组织感染及菌血症)的病因报告频率不断增加,但在人类中均为罕见细菌。下肢慢性感染和肝脏疾病已被确定为血流感染的危险因素,后者病程更快且预后更差。海藻希瓦氏菌似乎比腐败希瓦氏菌更具毒性。大多数人类腐败希瓦氏菌菌株是从细菌菌群中分离出来的,这使其临床意义受到质疑。由于常规检测中海藻希瓦氏菌很容易被误认为是腐败希瓦氏菌,因此必须使用分子生物学方法进行准确鉴定。