Persson A, Lingstrom P, van Dijken J W V
Dental Hygienist Education, Department of Odontology, University of Umeå, SE-90187 Umeå, Sweden.
Caries Res. 2005 May-Jun;39(3):201-6. doi: 10.1159/000084799.
The aim of this in vivo study was to evaluate the neutralizing capacity, registered as change of plaque acidogenicity, on aged proximal restorations of an ion-releasing composite resin (IRCR), which releases hydroxyl, calcium, and fluoride ions at low pH. Twenty patients, with a mean age of 63 years (range 43-85), participated. All had one aged proximal IRCR restoration (mean age 15 months) and one nonrestored enamel surface to make an intraindividual comparison possible. The neutralizing effect of the IRCR was evaluated by measuring plaque pH, using the microtouch method, after a mouthrinse with 10% sucrose. The plaque pH measurements were repeated 1.5 years later on the IRCR (mean age 34 months), the enamel surfaces and a universal hybrid composite resin (CR). At both 15 and 34 months, the plaque on the IRCR surfaces showed the least acidogenic potential for the whole 60-min time interval. The largest differences between the IRCR, CR and enamel were found during the first 15 min. At 15 months, the total areas under the plaque pH curve (AUC(5.7) and AUC(6.2)) differed significantly between the IRCR and enamel surfaces for the time periods 0-5 min and 5-15 min. At 34 months, significant differences were found between IRCR and CR at the 0- to 5-min time period. It can be concluded that IRCR restorations countered the plaque pH fall and maintained it at levels where less enamel and dentin demineralization can occur.
本体内研究的目的是评估一种在低pH值下释放羟基、钙和氟离子的离子释放复合树脂（IRCR）对老化邻面修复体的中和能力，该能力通过菌斑产酸性的变化来衡量。20名平均年龄为63岁（范围43 - 85岁）的患者参与了研究。所有患者均有一个老化的邻面IRCR修复体（平均年龄15个月）和一个未修复的釉质表面，以便进行个体内比较。使用微触法在10%蔗糖漱口后测量菌斑pH值，以此评估IRCR的中和效果。1.5年后，在IRCR（平均年龄34个月）、釉质表面和通用混合型复合树脂（CR）上重复进行菌斑pH值测量。在15个月和34个月时，IRCR表面的菌斑在整个60分钟时间间隔内产酸潜力最小。IRCR、CR和釉质之间的最大差异出现在最初的15分钟内。在15个月时，在0 - 5分钟和5 - 15分钟时间段内，IRCR和釉质表面之间的菌斑pH曲线下总面积（AUC(5.7)和AUC(6.2)）存在显著差异。在34个月时，在0 - 5分钟时间段内，IRCR和CR之间存在显著差异。可以得出结论，IRCR修复体能够对抗菌斑pH值下降，并将其维持在釉质和牙本质脱矿较少发生的水平。
