Persson Anitha, Claesson Rolf, Van Dijken Jan W V
Department of Odontology, Dental Hygienist Education, Dental School Umeå University, SE-901 87 Umea, Sweden.
Acta Odontol Scand. 2005 Feb;63(1):21-5. doi: 10.1080/00016350510019649.
The purpose of this in vivo study was to evaluate the cariogenic microflora of plaque on aged restorations of a hydroxyl, fluoride, and calcium ion-releasing composite resin (IRCR) (Ariston pHc), and to compare it intra-individually with a universal hybrid composite resin and enamel. Each of 19 subjects received one proximal restoration of the IRCR, one proximal universal hybrid composite resin restoration (CR) and each subject had one non-filled proximal enamel control surface to make intra-individual comparisons possible. To avoid peak ion releases from the materials, aged restorations were studied. Plaque was collected from 57 surfaces using sterile applicator tips. Samples were cultured to determine the numbers of mutans streptococci, lactobacilli, and total microorganisms. The relative numbers for mutans streptococci (% of total bacteria) were: IRCR 0.59%, CR 0.40%, enamel 0.22%. Two outliers were found in the IRCR group. Excluding these outliers resulted in a relative number of 0.33%. Lactobacilli were detected in the plaque from only 9 surfaces and at very low relative proportions for all three surfaces: 0.01%. The enamel surfaces showed the lowest relative numbers of mutans streptococci and lactobacilli, but the differences were not significant. It can be concluded that the ion release of the IRCR did not influence the growth of cariogenic microorganisms in dental plaque.
本体内研究的目的是评估含羟基、氟和钙离子释放复合树脂（IRCR）（Ariston pHc）的老年修复体上菌斑的致龋微生物群，并在个体内将其与通用混合型复合树脂和牙釉质进行比较。19名受试者每人接受一个IRCR近中修复体、一个近中通用混合型复合树脂修复体（CR），且每名受试者有一个未充填的近中牙釉质对照表面，以便进行个体内比较。为避免材料的离子释放峰值，研究了老化修复体。使用无菌涂抹器尖端从57个表面采集菌斑。对样本进行培养以确定变形链球菌、乳酸菌和总微生物的数量。变形链球菌的相对数量（占总细菌的百分比）分别为：IRCR为0.59%，CR为0.40%，牙釉质为0.22%。在IRCR组中发现两个异常值。排除这些异常值后，相对数量为0.33%。仅在9个表面的菌斑中检测到乳酸菌，且所有三个表面的相对比例都非常低：0.01%。牙釉质表面的变形链球菌和乳酸菌相对数量最低，但差异不显著。可以得出结论，IRCR的离子释放不会影响牙菌斑中致龋微生物的生长。
