Atala Anthony
Department of Urology, Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA.
Adv Biochem Eng Biotechnol. 2005;94:181-210. doi: 10.1007/b100004.
Patients suffering from a variety of urologic diseases may be treated with transplanted tissues and organs. However, there is a shortage of donor tissues and organs, which is worsening yearly owing to the ageing population. Scientists in the field of regenerative medicine and tissue engineering are applying the principles of cell transplantation, material science, and bioengineering to construct biological substitutes that will restore and maintain normal function in diseased and injured urologic tissues. This chapter reviews recent advances that have occurred in the regeneration of urologic organs and describes how these applications may offer novel therapies for patients with urologic disease.
患有各种泌尿系统疾病的患者可以接受移植组织和器官的治疗。然而,供体组织和器官短缺,并且由于人口老龄化,这种短缺状况逐年恶化。再生医学和组织工程领域的科学家们正在应用细胞移植、材料科学和生物工程的原理来构建生物替代品,以恢复和维持患病及受损泌尿系统组织的正常功能。本章回顾了泌尿系统器官再生方面的最新进展,并描述了这些应用如何为泌尿系统疾病患者提供新的治疗方法。