Wongtongkam Nualnong, Wilde Henry, Sitthi-Amorn Chitr, Ratanabanangkoon Kavi
The College of Public Health, Chulalongkorn University, Bangkok, Thailand.
Mil Med. 2005 Apr;170(4):336-41. doi: 10.7205/milmed.170.4.336.
This study evaluated factors affecting the severity of bite site necrosis and systemic symptoms resulting from envenomation among patients bitten by Thai cobras (Naja kaouthia) in Thailand. We studied 45 victims prospectively. An additional 40 medical records were obtained for a retrospective study. Collected data included gender of the victims, anatomic locations of bites, where attacks took place, and predisposing factors and how they might have affected the clinical course. Most patients were asymptomatic or mildly symptomatic. Neurotoxic symptoms and respiratory failure developed in 31.11% and 12.50% in the prospective and retrospective groups, respectively. Only one patient died, from the effects of prolonged respiratory failure. There was some degree of tissue necrosis at the bite site for almost all victims. One victim required amputation of a digit in the retrospective study, and 33.60% of the prospective group and 20% of the retrospective group required minor surgical debridement. Snakebites in Thailand are still a public health problem, although rapid urbanization has decreased the number of victims because of degradation of the snake's habitat.
本研究评估了泰国眼镜蛇(眼镜王蛇)咬伤泰国患者后,影响咬伤部位坏死严重程度及中毒所致全身症状的因素。我们对45名受害者进行了前瞻性研究。另外获取了40份医疗记录用于回顾性研究。收集的数据包括受害者的性别、咬伤的解剖位置、袭击发生地点、诱发因素以及这些因素可能如何影响临床病程。大多数患者无症状或症状轻微。前瞻性和回顾性研究组中,分别有31.11%和12.50%的患者出现神经毒性症状和呼吸衰竭。仅1例患者因长期呼吸衰竭死亡。几乎所有受害者的咬伤部位都有一定程度的组织坏死。在回顾性研究中有1名受害者需要截指,前瞻性研究组中有33.60%的患者和回顾性研究组中有20%的患者需要进行小手术清创。泰国的蛇咬伤仍是一个公共卫生问题,尽管快速城市化因蛇栖息地退化导致受害者数量减少。