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单眼镜蛇咬伤所致的麻痹和坏死性伤口感染

Paralysis and Necrotic Wound Infection Resulting From Monocled Cobra Envenomation.

作者信息

Sultan Danielle A, Angelakakis George, Braun Matthew C, DelBianco John D, Katz Kenneth D

机构信息

Department of Emergency and Hospital Medicine, Lehigh Valley Health Network/University of South Florida Morsani College of Medicine, Allentown, USA.

Department of Family Medicine, Northern Light-Eastern Maine Medical Center, Bangor, USA.

出版信息

Cureus. 2024 Nov 2;16(11):e72875. doi: 10.7759/cureus.72875. eCollection 2024 Nov.

Abstract

Non-native snake envenomations can be difficult to manage because of challenges obtaining appropriate antivenom and unfamiliarity with the expected clinical effects. This case report describes a 37-year-old man who was envenomated by his pet monocled cobra (). He experienced respiratory failure, requiring intubation and mechanical ventilation. Thai king cobra antivenom, recommended by a toxinologist consultant, was obtained from the nearby zoo and administered. The patient was extubated on hospital day (HD) 2. He returned to the hospital two days after initial discharge with worsening erythema, swelling, and purulent discharge from the bite wound. He was treated in the emergency department (ED) and started on intravenous vancomycin and cefepime. The wound culture report found and . The patient transitioned to oral antibiotics at discharge on HD 6. The wound developed an eschar, so he underwent debridement, fasciotomy and skin grafting on an outpatient basis. Thirty-six days post-envenomation, he achieved full functional recovery. This case demonstrates some of the challenges inherent to the management of envenomations by non-native snakes. Medical toxicologists and poison control centers can help to find appropriate antivenom and guide treatment.

摘要

由于获取合适抗蛇毒血清存在困难以及对预期临床效果不熟悉,非本地蛇咬伤的中毒情况可能难以处理。本病例报告描述了一名37岁男子被其宠物眼镜王蛇咬伤中毒的情况。他出现呼吸衰竭,需要插管和机械通气。在毒素学顾问的建议下,从附近动物园获取了泰国眼镜王蛇抗蛇毒血清并进行了注射。患者在住院第2天拔管。首次出院两天后,他因咬伤伤口处红斑、肿胀和脓性分泌物加重再次入院。他在急诊科接受治疗,并开始静脉注射万古霉素和头孢吡肟。伤口培养报告发现了……和……。患者在住院第6天出院时改用口服抗生素。伤口形成了焦痂,因此他在门诊接受了清创、筋膜切开术和皮肤移植。中毒后36天,他实现了完全功能恢复。本病例展示了非本地蛇咬伤中毒处理过程中固有的一些挑战。医学毒理学家和中毒控制中心可以帮助找到合适的抗蛇毒血清并指导治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9bf/11610033/1bb4c8400316/cureus-0016-00000072875-i01.jpg

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