Petereit Daniel G, Rogers Deborah, Burhansstipanov Linda, Kaur Judith, Govern Frank, Howard Steve P, Osburn Christen H, Coleman C Norman, Fowler Jack F, Chappell Richard, Mehta Minesh P
John T. Vucurevich Cancer Institute, Rapid City, SD 57701, USA.
J Cancer Educ. 2005 Spring;20(1 Suppl):65-70. doi: 10.1207/s15430154jce2001s_14.
The "Walking Forward" program is a scientific collaborative program between Rapid City Regional Hospital, the University of Wisconsin, the Mayo Clinic, and partnerships with the American Indian community in western South Dakota-3 reservations and 1 urban population. The purpose is to increase participation of health disparities populations on National Cancer Institute clinical trials as part of the Cancer Disparities Research Partnership program. Clinical practice suggests that Native American cancer patients present with more advanced stages of cancer and hence have lower cure rates and higher treatment-related morbidities. It is hypothesized that a conventional course of cancer treatment lasting 6 to 8 weeks may be a barrier.
Innovative clinical trials have been developed to shorten the course of treatment. A molecular predisposition to treatment side effects is also explored. These clinical endeavors will be performed in conjunction with a patient navigator research program.
Research metrics include analysis of process, clinical trials participation, treatment outcome, and assessment of access to cancer care at an early stage of disease.
“向前迈进”项目是拉皮德城地区医院、威斯康星大学、梅奥诊所之间的一项科学合作项目,并且与南达科他州西部的美洲印第安社区建立了伙伴关系——涉及3个保留地和1个城市人口。其目的是作为癌症差异研究伙伴关系项目的一部分,提高健康差异人群参与美国国立癌症研究所临床试验的比例。临床实践表明,美国原住民癌症患者的癌症分期更晚,因此治愈率更低,治疗相关发病率更高。据推测,持续6至8周的传统癌症治疗疗程可能是一个障碍。
已开展创新临床试验以缩短治疗疗程。还探索了治疗副作用的分子易感性。这些临床工作将与患者导航研究项目一起进行。
研究指标包括对过程、临床试验参与情况、治疗结果以及疾病早期癌症护理可及性的评估分析。