1972 - 1975年不列颠哥伦比亚省的唐氏综合征与母亲年龄
Down's syndrome and maternal age in British Columbia, 1972--75.
作者信息
Griffiths A J, Lowry R B, Renwick D H
出版信息
Environ Health Perspect. 1979 Aug;31:9-11. doi: 10.1289/ehp.79319.
Abstract
The occurrence of Down's syndrome in British Columbia during the period 1972-75 is analyzed with respect to maternal age distribution. This period is compared with previously studied periods. No marked trends are evident in the various age group-specific rates studied. The significance of these findings is discussed in connection with a possible role of environmental nutagens in induction of Down's syndrome and the maternal age effect.
摘要
对1972 - 1975年期间不列颠哥伦比亚省唐氏综合征的发病情况，就母亲年龄分布进行了分析。将这一时期与之前研究过的时期作了比较。在所研究的各个特定年龄组发病率中，未发现明显趋势。结合环境诱变剂在唐氏综合征诱发过程中可能发挥的作用以及母亲年龄效应，对这些研究结果的意义进行了讨论。
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