Jeong Jin-Yong, Yoon Hyun Jung, Kim Eun Sil, Lee Yoola, Choi Sang-Ho, Kim Nam Joong, Woo Jun Hee, Kim Yang Soo
Division of Infectious Diseases, Asan Medical Center and Asan Institute for Life Sciences, University of Ulsan College of Medicine, 388-1 Pungnap-dong, Songpa-gu, Seoul 138-736, Korea.
Antimicrob Agents Chemother. 2005 Jun;49(6):2522-4. doi: 10.1128/AAC.49.6.2522-2524.2005.
qnr was detected in 2 of 260 Escherichia coli clinical isolates collected from a Korean hospital during the period 2001 to 2003. The two strains were not clonally related. qnr was located in In4 family class 1 integrons of original structure, downstream of orf513 and upstream from another resistance gene (dfrA3b) and a gene of unknown function (orf105). Transfer of the qnr determinant by conjugation could be detected from only one strain.
在2001年至2003年期间从一家韩国医院收集的260株大肠杆菌临床分离株中,检测到2株携带qnr。这两株菌株没有克隆相关性。qnr位于原始结构的In4家族1类整合子中,在orf513下游,另一个耐药基因(dfrA3b)和一个功能未知基因(orf105)上游。仅从一株菌株中检测到通过接合转移的qnr决定簇。