Fontana M, Spertini F, Bart P A, Leimgruber A
Service d'immunologie et d'allergie, Département de médecine, CHUV, 1011 Lausanne.
Rev Med Suisse. 2005 Apr 13;1(15):1010, 1013-7.
To obtain a precise diagnosis of food allergy, it is essential to take a careful and detailed clinical history. This allows for directing further investigations and the patient should receive adequate information. In a research setting, recombinant allergens obtained by biotechnologies permit to reach a precise identification of allergenic proteins, with the hope of treating patients exclusively with the proteins to which they are allergic. In case of light reactions, a strict allergen avoidance is not required, but it is preferable to avoid the consumption of potentially dangerous food in isolated sites and before or during physical effort. In case of severe anaphylactic reactions with potent allergens like hazelnuts, peanuts and sea food, strict information about allergen avoidance and prescription of an emergency kit will be given.
为了获得食物过敏的准确诊断,仔细且详细地采集临床病史至关重要。这有助于指导进一步的检查,并且患者应得到充分的信息。在研究环境中,通过生物技术获得的重组变应原能够实现对变应原蛋白的精确鉴定,有望仅用患者过敏的蛋白来治疗患者。对于轻度反应,不需要严格避免接触变应原,但最好在孤立场所、体力活动之前或期间避免食用潜在危险的食物。对于如榛子、花生和海鲜等强效变应原引起的严重过敏反应,将提供关于避免接触变应原的严格信息以及应急包的处方。