Muñoz-Furlong Anne
The Food Allergy & Anaphylaxis Network, 11781 Lee Jackson Hgwy, Suite 160, Fairfax, VA 22033, USA.
Novartis Found Symp. 2004;257:265-74; discussion 274-5, 276-85.
It is estimated that dose to 7 million Americans have food allergy. The incidence of food allergy, particularly peanut allergy, is believed to be on the rise. Several studies have shown that in spite of a patient's best efforts to avoid ingesting the allergy-causing food, reactions will occur. These reactions occur from incorrect ingredient information in food service or restaurant settings, incorrect product labels, or mistakes in label reading. In the hospital setting, patients are sometimes treated for an anaphylactic reaction in the emergency room but are not given instructions to see a specialist to determine the cause of their reaction, nor are they given a prescription for epinephrine to arm them to treat future allergic emergencies. Two studies of fatal and near fatal allergic reactions concluded that a delay in administration of epinephrine could have been a factor in the fatal outcomes. However, schools often do not have written emergency action plans in place for children with documented food allergy, and patients and caregivers often report not knowing when to use the epinephrine kit or how to use it. Until there is a cure for food allergy and anaphylaxis, avoidance of the allergen is key. There is much work to be done in education and public policy regarding anaphylaxis.
据估计,700万美国人患有食物过敏症。食物过敏的发病率,尤其是花生过敏,据信正在上升。多项研究表明,尽管患者尽最大努力避免摄入引起过敏的食物,但仍会发生过敏反应。这些反应是由于食品服务或餐厅环境中成分信息错误、产品标签不正确或标签阅读错误导致的。在医院环境中,患者有时在急诊室接受过敏反应治疗,但没有得到去看专科医生以确定反应原因的指示,也没有得到肾上腺素的处方来应对未来的过敏紧急情况。两项关于致命和近乎致命过敏反应的研究得出结论,肾上腺素给药延迟可能是导致致命结果的一个因素。然而,学校通常没有为有食物过敏记录的儿童制定书面应急行动计划,患者和护理人员经常报告不知道何时使用肾上腺素试剂盒或如何使用它。在找到食物过敏和过敏反应的治愈方法之前,避免接触过敏原是关键。在关于过敏反应的教育和公共政策方面,还有很多工作要做。