Ferreres Franco J, Blanquer Olivas J, Dosdá Muñoz R, Carbonell Monleón N, Moreno Clari E, Pérez Sancho E
Servicio de Medicina Intensiva. Hospital Clínico Universitario de Valencia. Valencia. España.
Arch Bronconeumol. 2005 May;41(5):290-2. doi: 10.1016/s1579-2129(06)60223-1.
Nocardia is a gram-positive bacillus that infects mainly immunodepressed patients. Its association with lupus erythematosus has been described only occasionally and we have found no reports in the literature of an association between lupus and acute respiratory distress syndrome due to pulmonary nocardiosis. We present such a case and discuss the mechanisms that make this lung infection so virulent as well as its epidemiological and microbiological characteristics, clinical presentation, diagnosis, and treatment.
诺卡菌是一种革兰氏阳性杆菌,主要感染免疫功能低下的患者。其与红斑狼疮的关联仅偶尔有描述,而我们在文献中未发现狼疮与肺诺卡菌病所致急性呼吸窘迫综合征之间关联的报道。我们报告这样一例病例,并讨论使这种肺部感染具有如此强毒性的机制及其流行病学和微生物学特征、临床表现、诊断和治疗。