新加坡华人11个Y染色体短串联重复序列位点的群体研究。
Population study of 11 Y-chromosomal STR loci in Singapore Chinese.
作者信息
Tang June Sheau Wei, Wong Hang Yee, Syn Christopher Kiu Choong, Tan-Siew Wai Fun, Chow Shui Tse, Budowle Bruce
机构信息
DNA Profiling Laboratory, Centre for Forensic Science, Health Sciences Authority, 11 Outram Road, 169078 Singapore, Singapore.
出版信息
Forensic Sci Int. 2006 Apr 20;158(1):65-71. doi: 10.1016/j.forsciint.2005.04.009.
In this study of 212 unrelated Singapore Chinese males, allelic frequencies and gene diversities of 11 Y-chromosome specific STR loci (DYS19, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS385a/b, DYS438 and DYS439) were established. A total of 184 haplotypes were observed in the 212 individuals studied, of which 165 (89.67%) were unique. The most common haplotype was observed in five (2.35%) individuals. The overall haplotype diversity for the 11 Y-STR loci was 99.81%, and the discrimination capacity was 86.79%.
在这项针对212名无血缘关系的新加坡华裔男性的研究中，确定了11个Y染色体特异性STR位点（DYS19、DYS389I、DYS389II、DYS390、DYS391、DYS392、DYS393、DYS385a/b、DYS438和DYS439）的等位基因频率和基因多样性。在所研究的212名个体中总共观察到184种单倍型，其中165种（89.67%）是独特的。最常见的单倍型在5名（2.35%）个体中被观察到。11个Y-STR位点的总体单倍型多样性为99.81%，鉴别能力为86.79%。
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