Lin Stephanie C, Mousa Albeir, Bernheim Joshua, Dayal Rajeev, Henderson Peter, Hollenbeck Scott, Kent K Craig, Faries Peter L
Department of Vascular Surgery, New York Presbyterian Hospital, Cornell University, Weill Medical School and Columbia University, College of Physicians and Surgeons, New York, NY 10021, USA.
Vasc Endovascular Surg. 2005 May-Jun;39(3):273-9. doi: 10.1177/153857440503900309.
Phlegmasia cerulea dolens is a limb-threatening form of deep venous thrombosis and should be treated aggressively. The authors report a patient who presented with iliocaval and femoral deep venous thrombosis and posed an additional therapeutic challenge based on a recent history of heparin-induced thrombocytopenia. Catheter-directed pharmacologic thrombolysis and balloon venoplasty were applied in treatment. The direct thrombin inhibitor argatroban was used in place of heparin for concurrent anticoagulation. This multimodality endovascular approach (chemical and mechanical interventions) was successful in relieving the venous occlusion and salvaging the limb, while maintaining appropriate treatment for heparin-induced thrombocytopenia.
股青肿是一种可威胁肢体的深静脉血栓形成形式，应积极治疗。作者报告了一名患者，该患者表现为髂股深静脉血栓形成，且由于近期有肝素诱导的血小板减少症病史，给治疗带来了额外挑战。采用了导管导向药物溶栓和球囊血管成形术进行治疗。使用直接凝血酶抑制剂阿加曲班代替肝素进行同期抗凝。这种多模式血管内治疗方法（化学和机械干预）成功缓解了静脉闭塞并挽救了肢体，同时对肝素诱导的血小板减少症进行了适当治疗。
