Goodnough Lawrence T
Department of Pathology, Stanford University School of Medicine, 300 Pasteur Drive, H-1402 Stanford, CA 94305-5324, USA.
Anesthesiol Clin North Am. 2005 Jun;23(2):241-52, v. doi: 10.1016/j.atc.2004.07.004.
This article discusses advances in blood safety during the last 20 years, particularly for prevention of transfusion-transmitted viral infections. Although the most serious known risks from blood transfusion are administrative errors, transfusion-related acute lung injury, and bacterial contamination in platelet products, infection from emerging pathogens such as West Nile virus emphasizes the need for implementing proactive strategies. Pathogen inactivation technologies and reactive strategies such as nucleic acid testing ensure continued advances in blood safety.
本文讨论了过去20年血液安全方面的进展，尤其是在预防输血传播病毒感染方面。尽管已知输血最严重的风险是管理失误、输血相关急性肺损伤和血小板制品中的细菌污染，但来自西尼罗河病毒等新出现病原体的感染凸显了实施积极策略的必要性。病原体灭活技术和核酸检测等反应性策略确保了血液安全的持续进步。
