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临时左心室起搏可改善心脏手术后需要心外膜起搏患者的血流动力学表现。

Temporary left ventricular pacing improves haemodynamic performance in patients requiring epicardial pacing post cardiac surgery.

作者信息

Flynn Michael J, McComb Janet M, Dark John Henry

机构信息

Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle-on-Tyne, NE7 7DN, UK.

出版信息

Eur J Cardiothorac Surg. 2005 Aug;28(2):250-3. doi: 10.1016/j.ejcts.2005.03.019.

Abstract

OBJECTIVE

In the 1990s, sequential atrio-ventricular pacing demonstrated haemodynamic benefit relative to right ventricular pacing in patients with sinus rhythm requiring pacing post cardiopulmonary bypass. The benefit of biventricular pacing has been demonstrated in non-surgical patients with severe left ventricular dysfunction. It was hypothesised that left ventricular pacing would increase cardiac output in surgical patients. We report the findings of a prospective trial of left ventricular pacing with active lead placement on the anterior or posterior left ventricular surface, compared to standard practice of active lead placement on the right ventricular surface.

METHODS

Twenty five patients with left ventricular dysfunction underwent pacing with active lead placement on the right ventricle (control), the anterior left ventricle and the posterior left ventricle in random order, with each pacing mode of 10 min duration, following cardiopulmonary bypass. Haemodynamic parameters were measured with a thermodilution pulmonary artery catheter. Patients provided their control values.

RESULTS

In the 25 patients studied, pacing with the active lead posteriorly on the left ventricle increased cardiac index from 2.74 to 3.08 l/min per m2 (P=0.019). Significant increases in mean arterial pressure with the use of this pacing mode were observed. There were no complications relating to application or removal of the left ventricle pacing leads.

CONCLUSIONS

Left ventricular pacing with active lead placed on the postero-lateral left ventricular wall affords haemodynamic benefit to cardiac surgical patients.

摘要

目的

在20世纪90年代,对于体外循环后需要起搏的窦性心律患者,序贯房室起搏相对于右心室起搏显示出血流动力学益处。双心室起搏的益处已在严重左心室功能不全的非手术患者中得到证实。据推测,左心室起搏会增加手术患者的心输出量。我们报告了一项前瞻性试验的结果,该试验将主动电极置于左心室前表面或后表面进行左心室起搏,与将主动电极置于右心室表面的标准做法进行比较。

方法

25例左心室功能不全患者在体外循环后,随机顺序接受右心室(对照)、左心室前表面和左心室后表面的主动电极起搏,每种起搏模式持续10分钟。用热稀释肺动脉导管测量血流动力学参数。患者提供其对照值。

结果

在研究的25例患者中,将主动电极置于左心室后表面起搏使心脏指数从2.74升/分钟每平方米增加到3.08升/分钟每平方米(P = 0.019)。观察到使用这种起搏模式时平均动脉压显著升高。左心室起搏电极的应用或移除未出现并发症。

结论

将主动电极置于左心室后外侧壁进行左心室起搏可为心脏手术患者带来血流动力学益处。

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