Guízar Juan-Manuel, Ahuatzin Rosalía, Amador Norma, Sánchez Guillermo, Romer Gustavo
Epidemiological Research Unit, Mexican Institute of Social Security, Leon, Mexico.
Indian Pediatr. 2005 May;42(5):464-9.
We compared factors associated with sympathetic cardiac activity in 70 male adolescents (34 obese and 36 with appropriate weight). In fasting we measured insulin, leptin, glucose, blood pressure, and heart rate variability by power spectral analysis. Obese adolescents had higher values for systolic blood pressure, insulin, leptin, low frequency/high frequency index (LF/HF); and lower for standard deviation of all the normal RR intervals, and total power. In the multiple regression analysis, factors associated with LF/HF index were leptin and systolic blood pressure (R2 = 0.18; P = 0.004 for the model). We concluded that higher sympathetic activity in obese adolescents is related to higher leptin and systolic blood pressure levels..
我们比较了70名男性青少年（34名肥胖青少年和36名体重正常青少年）中与交感神经心脏活动相关的因素。在空腹状态下，我们通过功率谱分析测量了胰岛素、瘦素、血糖、血压和心率变异性。肥胖青少年的收缩压、胰岛素、瘦素、低频/高频指数（LF/HF）值较高；而所有正常RR间期的标准差和总功率较低。在多元回归分析中，与LF/HF指数相关的因素是瘦素和收缩压（模型的R2 = 0.18；P = 0.004）。我们得出结论，肥胖青少年较高的交感神经活动与较高的瘦素和收缩压水平有关。
