Rynnel-Dagöö B, Lindberg K, Bagger-Sjöbäck D, Larson O
Department of Otorhinolaryngology, Huddinge University Hospital, Sweden.
Int J Pediatr Otorhinolaryngol. 1992 May;23(3):201-9. doi: 10.1016/0165-5876(92)90101-t.
Fourty-four cleft palate children consecutively referred to a plastic surgery unit were treated with palate repair at one year of age by one surgeon. The children were not routinely treated with ventilating tubes for middle ear disease. At 3 years of age they were investigated for aural pathology. Also specific antipneumococcal antibody activity was measured and was found to be compatible with the activity found in healthy age-matched control children. In the cleft palate children with no immaturity of the immune system only a slight increase in frequency of acute otitis media was evident. One third of the children had however suffered from long-standing secretory otitis media which can be regarded to be more common than what has been found in the normal population in several epidemiologic studies. At 3-4 years of age 82% of the children had a normal hearing indicating an improvement of the condition.
连续转诊至整形外科的44名腭裂患儿在1岁时由一名外科医生进行了腭裂修复治疗。这些患儿未常规接受治疗中耳疾病的通气管。在3岁时，对他们进行了耳部病理学检查。还测量了特异性抗肺炎球菌抗体活性，发现其与年龄匹配的健康对照儿童中的活性相符。在免疫系统未发育不成熟的腭裂患儿中，急性中耳炎的发病率仅略有增加。然而，三分之一的患儿患有长期分泌性中耳炎，这在一些流行病学研究中被认为比正常人群中更为常见。在3至4岁时，82%的患儿听力正常，表明病情有所改善。
