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腭裂儿童中耳疾病的腺样体切除术:系统评价。

Adenoidectomy for middle ear disease in cleft palate children: a systematic review.

机构信息

Otolaryngology Unit, Department of Health Sciences, Santi Paolo E Carlo Hospital, Università Degli Studi Di Milano, Via Antonio di Rudinì, 8, 20142, Milan, Italy.

出版信息

Eur Arch Otorhinolaryngol. 2022 Mar;279(3):1175-1180. doi: 10.1007/s00405-021-07035-6. Epub 2021 Aug 28.

Abstract

PURPOSE

Cleft palate children have a higher incidence of otitis media with effusion, more frequent recurrent acute otitis media episodes, and worse conductive hearing losses than non-cleft children. Nevertheless, data on adenoidectomy for middle ear disease in this patient group are scarce, since many feared worsening of velopharyngeal insufficiency after the procedure. This review aims at collecting the available evidence on this subject, to frame possible further areas of research and interventions.

METHODS

A PRISMA-compliant systematic review was performed. Multiple databases were searched with criteria designed to include all studies focusing on the role of adenoidectomy in treating middle ear disease in cleft palate children. After duplicate removal, abstract and full-text selection, and quality assessment, we reviewed eligible articles for clinical indications and outcomes.

RESULTS

Among 321 unique citations, 3 studies published between 1964 and 1972 (2 case series and a retrospective cohort study) were deemed eligible, with 136 treated patients. The outcomes were positive in all three articles in terms of conductive hearing loss improvement, recurrent otitis media episodes reduction, and effusive otitis media resolution.

CONCLUSION

Despite promising results, research on adenoidectomy in treating middle ear disease in the cleft population has stopped in the mid-Seventies. No data are, therefore, available on the role of modern conservative adenoidectomy techniques (endoscopic and/or partial) in this context. Prospective studies are required to define the role of adenoidectomy in cleft children, most interestingly in specific subgroups such as patients requiring re-tympanostomy, given their known risk of otologic sequelae.

摘要

目的

腭裂儿童患分泌性中耳炎的发病率较高,复发性急性中耳炎发作更为频繁,传导性听力损失更为严重。然而,由于许多人担心手术后会导致腭咽闭合不全加重,因此针对该患者群体中耳疾病行腺样体切除术的数据很少。本综述旨在收集这一主题的现有证据,为进一步的研究和干预措施提供依据。

方法

本研究采用 PRISMA 一致性系统评价方法。设计了特定的标准,以纳入所有关注腭裂儿童中耳疾病腺样体切除术作用的研究,通过多个数据库进行搜索。在去除重复项、摘要和全文选择以及质量评估后,我们对符合条件的文章进行了临床适应证和结局的综述。

结果

在 321 篇独特的引文中有 3 篇研究符合入选标准,发表于 1964 年至 1972 年期间,均为病例系列和回顾性队列研究,共纳入 136 例接受治疗的患者。三篇文章均报道了积极的结果,包括改善传导性听力损失、减少复发性中耳炎发作和解决分泌性中耳炎。

结论

尽管结果有一定的前景,但 70 年代中期,针对腭裂人群中耳疾病行腺样体切除术的研究已经停止。因此,在这种情况下,没有关于现代保守性腺样体切除术技术(内镜和/或部分)作用的数据。需要进行前瞻性研究来确定腺样体切除术在腭裂儿童中的作用,特别是在需要再次鼓室切开术的特定亚组患者中,因为他们已知存在耳科后遗症的风险。

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