Kimberlin David W
Department of Pediatrics, Division of Pediatric Infectious Diseases, The University of Alabama, Birmingham, AL 35233, USA.
Pediatr Clin North Am. 2005 Jun;52(3):837-67, vii. doi: 10.1016/j.pcl.2005.02.006.
The increase in the number and classes of antiviral agents that has occurred since the 1980s is remarkable. The rapid expansion in therapeutic options for previously untreatable illnesses challenges clinicians to gain familiarity and experience with these new drugs, especially with regard to their use in children. This article describes the clinical utilities, pharmacokinetics, and adverse effects of these new drugs to empower practitioners to use them appropriately.
自20世纪80年代以来，抗病毒药物的数量和种类显著增加。针对以前无法治疗的疾病，治疗选择迅速扩大，这就要求临床医生熟悉并掌握这些新药，尤其是在儿童用药方面。本文介绍了这些新药的临床应用、药代动力学和不良反应，以使从业者能够合理使用它们。
