Luda E, Sicuro L, Albera R, Roberto C, De Lucchi R
Dipartimento di Emergenza ed Accettazione Neurologica, Ospedale Molinette, Torino.
Ital J Neurol Sci. 1992 Mar;13(2):119-24. doi: 10.1007/BF02226959.
Retraction-convergence nystagmus is a classic finding in extensive and bilateral lesions of the dorsal midbrain, usually neoplastic and, as such, considered to signal a poor prognosis. We report 4 cases of retraction-convergence nystagmus associated with Parinaud syndrome arising from circumscribed lesions of vascular origin--3 hemorrhagic and 1 ischemic--with a completely benign course. The neuroimaging study enabled us to identify involvement of the pretectal areas and posterior commissure as well as of the dorsomedial thalamic nuclei in all cases. It thus seems that one or more of these areas must be involved in the genesis of this nystagmus.
退缩-会聚性眼球震颤是中脑背侧广泛双侧病变的典型表现，通常为肿瘤性病变，因此被认为预示预后不良。我们报告4例由血管源性局限性病变（3例出血性和1例缺血性）引起的与帕里诺综合征相关的退缩-会聚性眼球震颤病例，其病程完全良性。神经影像学研究使我们能够在所有病例中确定顶盖前区、后连合以及丘脑背内侧核的受累情况。因此，似乎这些区域中的一个或多个必定参与了这种眼球震颤的发生。
