Smrkovski L L, Larson C L, Reed S G
Infect Immun. 1979 Sep;25(3):1078-80. doi: 10.1128/iai.25.3.1078-1080.1979.
Congenitally athymic mice were more susceptible to challenge with amastigotes of Leishmania donovani than were their thymus-intact littermates. This increased susceptibility correlated with a lack of Arthus and delayed-type responses when animals were skin tested with leishmanial antigen.
先天性无胸腺小鼠比其胸腺完整的同窝小鼠更容易受到杜氏利什曼原虫无鞭毛体的攻击。当用利什曼原虫抗原对动物进行皮肤试验时,这种易感性增加与缺乏阿瑟斯反应和迟发型反应相关。