Mizuki Y, Kajimura N, Kai S, Suetsugi M, Ushijima I, Yamada M
Department of Neuropsychiatry, Yamaguchi University School of Medicine, Ube, Japan.
Int J Psychophysiol. 1992 Mar;12(2):169-78. doi: 10.1016/0167-8760(92)90008-y.
The distinct EEG theta rhythm from the frontal midline area observed during performance of mental tasks has been called Fm theta. In the present study, plasma catecholamine responses to mental stress were investigated using male students with (n = 12) and without (n = 12) Fm theta. The subjects were requested to complete the trait anxiety scale of STAI, and control blood samples were obtained. 65 min later, their EEGs were recorded during performance of an arithmetic addition task for 5 min. The state anxiety scores of STAI were obtained twice before and after the EEG recording. Blood samples were drawn three times during the state anxiety test and the EEG recording. The Fm theta appearance group showed low trait anxiety and a decrease of state anxiety after the mental task; however, the Fm theta non-appearance group exhibited high trait anxiety and no changes of state anxiety before and after the mental task. The concentrations of DA, HVA, NA and MHPG in the Fm theta appearance group showed lower levels at all times compared to those in the non-appearance group. In the Fm theta appearance group, an increase of DA turnover was observed by the addition of mental task. On the other hand, the Fm theta non-appearance group showed an increase of NA turnover.
在执行心理任务期间从额中线区域观察到的独特脑电图θ节律被称为Fmθ。在本研究中，使用有Fmθ（n = 12）和无Fmθ（n = 12）的男学生研究了血浆儿茶酚胺对心理应激的反应。要求受试者完成状态-特质焦虑量表（STAI）的特质焦虑量表部分，并采集对照血样。65分钟后，在他们执行5分钟算术加法任务期间记录脑电图。在脑电图记录之前和之后两次获取STAI的状态焦虑评分。在状态焦虑测试和脑电图记录期间三次采集血样。Fmθ出现组表现出低特质焦虑，并且在心理任务后状态焦虑降低；然而，Fmθ未出现组表现出高特质焦虑，并且在心理任务前后状态焦虑没有变化。与未出现组相比，Fmθ出现组中多巴胺（DA）、高香草酸（HVA）、去甲肾上腺素（NA）和3-甲氧基-4-羟基苯乙二醇（MHPG）的浓度在所有时间都较低。在Fmθ出现组中，通过增加心理任务观察到DA周转率增加。另一方面，Fmθ未出现组显示NA周转率增加。
