电子转移反应中的偕二烷基效应：通过电化学环化快速合成七元环。

The gem-dialkyl effect in electron transfer reactions: rapid synthesis of seven-membered rings through an electrochemical annulation.

作者信息

Sperry Jeffrey B, Wright Dennis L

机构信息

Department of Chemistry, Dartmouth College, Hanover, New Hampshire 03755, USA.

出版信息

J Am Chem Soc. 2005 Jun 8;127(22):8034-5. doi: 10.1021/ja051826+.

DOI:10.1021/ja051826+

PMID:15926826

Abstract

An electrochemical furan annulation strategy has been developed for the synthesis of seven-membered rings. Key to the success of the annulation is the placement of a gem-dialkyl group in the tether. Voltammetric studies indicate that this effect lowers the oxidation potential by approximately 110 mV.

摘要

已开发出一种用于合成七元环的电化学呋喃环化策略。环化成功的关键在于在连接链中引入偕二烷基。伏安法研究表明，这种效应使氧化电位降低了约110毫伏。