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LY264826联合庆大霉素与万古霉素联合庆大霉素对血培养分离出的肠球菌的比较。

Comparison of LY264826-gentamicin with vancomycin-gentamicin against enterococci from blood cultures.

作者信息

Watanakunakorn C

机构信息

Department of Internal Medicine, St. Elizabeth Hospital Medical Center, Youngstown, Ohio 44501.

出版信息

J Antimicrob Chemother. 1992 Mar;29(3):303-6. doi: 10.1093/jac/29.3.303.

DOI:10.1093/jac/29.3.303
PMID:1592699
Abstract

The combination of the new glycopeptide LY264826 and gentamicin was compared with the combination of vancomycin and gentamicin against 30 strains of enterococci, comprising 20 strains of Enterococcus faecalis, five strains of Enterococcus faecium and five strains of Enterococcus avium, isolated from blood cultures. LY264826 plus gentamicin was synergic against E. faecalis and E. faecium, but not against E. avium.

摘要

将新型糖肽类抗生素LY264826与庆大霉素的联合用药，和万古霉素与庆大霉素的联合用药相比较，用于对抗从血培养中分离出的30株肠球菌，其中包括20株粪肠球菌、5株屎肠球菌和5株鸟肠球菌。LY264826加庆大霉素对粪肠球菌和屎肠球菌具有协同作用，但对鸟肠球菌无协同作用。

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