枯草芽孢杆菌芽孢形成σ因子前体区域的突变
Mutations in the precursor region of a Bacillus subtilis sporulation sigma factor.
作者信息
Rong S, Sonenshein A L
机构信息
Department of Molecular Biology and Microbiology, Tufts University Health Sciences Campus, Boston, Massachusetts 02111.
出版信息
J Bacteriol. 1992 Jun;174(11):3812-7. doi: 10.1128/jb.174.11.3812-3817.1992.
Abstract
Transcription from some sporulation-specific promoters of Bacillus subtilis is dependent on synthesis of pro-sigma E and its conversion to sigma E by proteolysis. Certain mutations in the precursor region of sigE, the gene encoding pro-sigma E, apparently allow the mutant sigE products to be active as sigma factors without being proteolysed in the normal way.
摘要
枯草芽孢杆菌某些芽孢形成特异性启动子的转录依赖于前体σE的合成及其通过蛋白水解转化为σE。编码前体σE的基因sigE的前体区域中的某些突变显然允许突变的sigE产物作为σ因子具有活性，而无需以正常方式进行蛋白水解。
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