Nagaraja P A, Mathew T, Shetty D P
Department of Microbiology, Narayana Hrudayalaya, Bangalore, India.
Indian J Med Microbiol. 2005 Apr;23(2):139-40. doi: 10.4103/0255-0857.16059.
The incidence of endocarditis produced by the so-called "opportunists" as a complication of prosthetic valve surgery is progressively increasing in frequency and gradually transforming the clinical picture habitually associated with this disease. Candida endocarditis is an unusual but severe complication caused by Candida albicans or other fungal species. This case and a review of the literature indicate that Candida endocarditis treated with amphotericin B and prosthetic valve replacement may recur months after treatment, and that late recurrent Candida endocarditis, which is difficult to diagnose and treat, may be best prevented by lifelong antifungal suppressive therapy.
由所谓“机会致病菌”作为人工瓣膜手术并发症所致的心内膜炎发病率日益上升，并逐渐改变了与该疾病相关的惯常临床症状。念珠菌性心内膜炎是由白色念珠菌或其他真菌引起的一种罕见但严重的并发症。本病例及文献回顾表明，接受两性霉素B治疗及人工瓣膜置换术的念珠菌性心内膜炎可能在治疗数月后复发，而难以诊断和治疗的晚期复发性念珠菌性心内膜炎，可能通过终身抗真菌抑制疗法得到最佳预防。
