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磁刺激的批判性综述:其在盆底功能障碍管理中的作用是什么?

A critical review on magnetic stimulation: what is its role in the management of pelvic floor disorders?

作者信息

Quek Pearllyn

机构信息

Department of Urology, Changi General Hospital, Singapore 529889.

出版信息

Curr Opin Urol. 2005 Jul;15(4):231-5. doi: 10.1097/01.mou.0000172395.54643.4d.

Abstract

PURPOSE OF REVIEW

This review looks at the acute effects of magnetic stimulation on urodynamic parameters and reviews the data on its use in the management of urinary incontinence.

RECENT FINDINGS

Reported cure rates for stress incontinence immediately after a course of perineal magnetic stimulation range from 12.5 to 52.9% with good improvement occurring in 32% to 41%. However the effect seems temporary and dependent on the number of sessions. Sacral and pelvic floor magnetic stimulation have also been shown to increase cystometric capacity, inhibit detrusor overactivity and resolve overactive bladder symptoms acutely. Persistence of this effect with symptomatic improvement one week after sacral magnetic stimulation has been demonstrated. How magnetic stimulation suppresses detrusor contraction is not known. Prospective trials with the Neocontrol chair (Neotonus Inc, Marietta, Georgia, USA) also showed symptomatic improvement in 71 to 87% in the short term. However, the longer term data appear mixed.

SUMMARY

Overall, the data available vary too much in terms of treatment protocols, patient mix and symptom severity to determine which group of patients might benefit most and what the optimal stimulation parameters are for each condition. Mean reductions in leak parameters, although statistically significant, may not always be clinically satisfactory. The beneficial effects also appear to be temporary and continuous treatment will probably be required. Further trials are needed to determine the optimum stimulation protocols for different situations and to compare magnetic stimulation with other forms of conservative pelvic floor therapy.

摘要

综述目的

本综述探讨磁刺激对尿动力学参数的急性影响,并回顾其在尿失禁管理中的应用数据。

最新发现

据报道,会阴磁刺激疗程结束后,压力性尿失禁的即刻治愈率为12.5%至52.9%,32%至41%的患者有明显改善。然而,这种效果似乎是暂时的,且取决于治疗次数。骶神经和盆底磁刺激也已显示可增加膀胱测压容量,抑制逼尿肌过度活动,并急性缓解膀胱过度活动症症状。已证实骶神经磁刺激一周后这种效果持续存在且症状有所改善。磁刺激如何抑制逼尿肌收缩尚不清楚。使用Neocontrol椅(Neotonus公司,美国佐治亚州玛丽埃塔)进行的前瞻性试验在短期内也显示71%至87%的患者症状有改善。然而,长期数据好坏参半。

总结

总体而言,现有数据在治疗方案、患者构成和症状严重程度方面差异太大,无法确定哪组患者可能受益最大,以及每种情况的最佳刺激参数是什么。漏尿参数的平均降低虽然具有统计学意义,但在临床上可能并不总是令人满意。有益效果似乎也是暂时的,可能需要持续治疗。需要进一步试验来确定不同情况下的最佳刺激方案,并将磁刺激与其他形式的保守盆底治疗进行比较。

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