Dinis Paulo Borges, Martins Maria Luz, Subtil João
Department of Otorhinolaryngology, Hospital de Pulido Valente, Lisbon.
Ear Nose Throat J. 2005 Apr;84(4):238-40.
Persistent isolated inflammation of the sphenoid sinus, an entity that is not diagnosed very often, poses a challenge to clinicians and researchers alike. Its features tend to suggest that its etiopathogenesis is different from that of more common forms of chronic rhinosinusitis. We report the case of a 54-year-old woman who had a history of distressing chronic postnasal drip and a globus sensation with opacification of the sphenoid sinus. She was diagnosed with gastroesophageal reflux, and Helicobacter pylori was detected in her gastric contents and in the inflamed mucosa of the sphenoid sinus, as well. Complete symptom relief was achieved only after she had undergone surgical sphenoidotomy and treatment with anti-H pylori medication. We discuss the potential for this ubiquitous gastric bacterium to play a role in at least some forms of chronic sinonasal inflammation.
蝶窦持续性孤立性炎症这种情况并不常被诊断出来，这对临床医生和研究人员来说都是一个挑战。其特征往往表明其病因发病机制与更常见的慢性鼻-鼻窦炎形式不同。我们报告一例54岁女性病例，她有令人苦恼的慢性鼻后滴漏病史以及咽喉部异物感，蝶窦出现浑浊。她被诊断为胃食管反流，在其胃内容物以及蝶窦发炎的黏膜中也检测到了幽门螺杆菌。仅在她接受蝶窦切开手术并使用抗幽门螺杆菌药物治疗后，症状才完全缓解。我们讨论了这种普遍存在的胃部细菌在至少某些形式的慢性鼻窦炎症中发挥作用的可能性。
